ID   C7M853_CAPOD            Unreviewed;       721 AA.
AC   C7M853;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   RecName: Full=Dipeptidyl-peptidase {ECO:0000256|RuleBase:RU366067};
DE            EC=3.4.14.- {ECO:0000256|RuleBase:RU366067};
GN   OrderedLocusNames=Coch_1768 {ECO:0000313|EMBL:ACU93313.1};
OS   Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / NCTC
OS   12371 / VPI 2845) (Bacteroides ochraceus).
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Capnocytophaga.
OX   NCBI_TaxID=521097 {ECO:0000313|EMBL:ACU93313.1, ECO:0000313|Proteomes:UP000006650};
RN   [1] {ECO:0000313|EMBL:ACU93313.1, ECO:0000313|Proteomes:UP000006650}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27872 / DSM 7271 / JCM 12966 / VPI 2845
RC   {ECO:0000313|Proteomes:UP000006650};
RX   PubMed=21304645; DOI=10.4056/sigs.15195;
RA   Mavrommatis K., Gronow S., Saunders E., Land M., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Nolan M., Lucas S., Chen F., Tice H., Cheng J.F.,
RA   Bruce D., Goodwin L., Pitluck S., Pati A., Ivanova N., Chen A.,
RA   Palaniappan K., Chain P., Hauser L., Chang Y.J., Jeffries C.D., Brettin T.,
RA   Detter J.C., Han C., Bristow J., Goker M., Rohde M., Eisen J.A.,
RA   Markowitz V., Kyrpides N.C., Klenk H.P., Hugenholtz P.;
RT   "Complete genome sequence of Capnocytophaga ochracea type strain (VPI
RT   2845).";
RL   Stand. Genomic Sci. 1:101-109(2009).
CC   -!- FUNCTION: Catalyzes the removal of dipeptides from the N-terminus of
CC       oligopeptides. {ECO:0000256|RuleBase:RU366067}.
CC   -!- SIMILARITY: Belongs to the peptidase S46 family.
CC       {ECO:0000256|ARBA:ARBA00010491, ECO:0000256|RuleBase:RU366067}.
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DR   EMBL; CP001632; ACU93313.1; -; Genomic_DNA.
DR   RefSeq; WP_015782816.1; NC_013162.1.
DR   AlphaFoldDB; C7M853; -.
DR   STRING; 521097.Coch_1768; -.
DR   MEROPS; S46.002; -.
DR   GeneID; 29675370; -.
DR   KEGG; coc:Coch_1768; -.
DR   eggNOG; COG3591; Bacteria.
DR   HOGENOM; CLU_013776_0_0_10; -.
DR   Proteomes; UP000006650; Chromosome.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0070009; F:serine-type aminopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043171; P:peptide catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR   InterPro; IPR019500; Pep_S46.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   PANTHER; PTHR38469; -; 1.
DR   PANTHER; PTHR38469:SF1; PERIPLASMIC PEPTIDASE SUBFAMILY S1B; 1.
DR   Pfam; PF10459; Peptidase_S46; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000256|RuleBase:RU366067}; Hydrolase {ECO:0000256|RuleBase:RU366067};
KW   Protease {ECO:0000256|RuleBase:RU366067};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006650};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW   ECO:0000256|RuleBase:RU366067}.
SQ   SEQUENCE   721 AA;  82242 MW;  3FF76DD9E0345AAD CRC64;
     MKKISLILLA FLLLTPIAKA DEGMWFLMFI ERLNQRDMQK LGLQLTAQEI YSINNNSLKD
     AIVQFNGGCT ASIISKDGLV LTNHHCGYGN IAQLSTPENN HLKNGFWARS HAEELSPKQS
     FVRFFVRMDN VTDRMLSVVK PSMNEKEREA ALNQEMAKIQ KENSEGGKYV VSVRPFFQGN
     EYYYFVYQDF KDVRLVGTPP ESIGKFGGDT DNWEWPRQTG DFSLFRVYTD KDGNAADYSP
     NNVPLKAKRY LKVSLKGVQD KDFAMIMGYP GRTNRWESSY WVDQNVKYAY PAWVEASKTA
     MDAMKRFMDK DDAVRLQYAS QYSSIANYWK NRQGMIDALT AHKTAATKRK TEAIFAKWAN
     KAENKAEYGD VLNTLSNFFE KTNAKSADEN YLGMLWRASF FVKIPTRYIS LVSNAKKGGM
     PTDELEKRVD DLLTEYDKVN LDVEKAILAD MLKLYTNKGT DVPSELKTIK TQYKGDFNKY
     VEELLAKSIY RSKETAKEGV FPKNKVFQNE KQINMALASD PILALSIALF VNYRNPSEEQ
     LSLEDSYAKA FRKFIKGMRD SKISTILYPD ANSTLRLTYG TVIPLAADKR NPDVKKNYYT
     TFNTLMAKYK KGDAEFDMPQ RMLDLYKKKE FGRYIDKDGS MHVNFLTNND ITGGNSGSPV
     MNGKGELIGL AFDGNIEAMA GDVIFDKQLQ RTINVDIRYV LWVIDIYAGA KNIINEIETV
     Q
//