ID   C8P8D4_9LACO            Unreviewed;       286 AA.
AC   C8P8D4;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   24-JAN-2024, entry version 55.
DE   SubName: Full=3-beta hydroxysteroid dehydrogenase/isomerase family protein {ECO:0000313|EMBL:EEW53232.1};
DE            EC=1.-.-.- {ECO:0000313|EMBL:EEW53232.1};
GN   ORFNames=HMPREF0494_1578 {ECO:0000313|EMBL:EEW53232.1};
OS   Limosilactobacillus antri DSM 16041.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Limosilactobacillus.
OX   NCBI_TaxID=525309 {ECO:0000313|EMBL:EEW53232.1, ECO:0000313|Proteomes:UP000003675};
RN   [1] {ECO:0000313|EMBL:EEW53232.1, ECO:0000313|Proteomes:UP000003675}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16041 {ECO:0000313|EMBL:EEW53232.1,
RC   ECO:0000313|Proteomes:UP000003675};
RA   Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA   Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA   Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA   Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA   Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA   Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA   Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA   Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA   Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA   Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL   Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEW53232.1}.
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DR   EMBL; ACLL01000045; EEW53232.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8P8D4; -.
DR   STRING; 525309.HMPREF0494_1578; -.
DR   PATRIC; fig|525309.8.peg.997; -.
DR   eggNOG; COG0702; Bacteria.
DR   HOGENOM; CLU_007383_10_7_9; -.
DR   OrthoDB; 152510at2; -.
DR   Proteomes; UP000003675; Unassembled WGS sequence.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd05269; TMR_SDR_a; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR47129:SF1; NMRA DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47129; QUINONE OXIDOREDUCTASE 2; 1.
DR   Pfam; PF13460; NAD_binding_10; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:EEW53232.1};
KW   Oxidoreductase {ECO:0000313|EMBL:EEW53232.1}.
FT   DOMAIN          7..186
FT                   /note="NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF13460"
SQ   SEQUENCE   286 AA;  31674 MW;  B102739BFAE45989 CRC64;
     MKYLITGATG HLGGMVVTEL SKLVPMDELR LGVHRLEKAG ALQAAGYEVV ALDYTDVDSM
     TAALTGVDVL VYIPSLTYQV QQRISEFENT LTAMQRANVT TIVAMSFIAD QYNNPFQMAS
     YYAYLPARLA SSGLNYAVVK NALYADPLVP YLPELIARQN VIYPVGNQAM SFISREDSAE
     ALARIAVQPY LHDHGQNYLL TMKQNYNMVE LSAIMSQVTG KQIGYAPVTL QEFADLYRSE
     GDGDELASMY HAAALGLMDE VTTDFQHITG HAPQSMTEYL TRHYQK
//