ID C8PD82_9LACO Unreviewed; 381 AA.
AC C8PD82;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Aminotransferase, class V {ECO:0000313|EMBL:EEW51555.1};
DE EC=2.8.1.7 {ECO:0000313|EMBL:EEW51555.1};
GN Name=iscS {ECO:0000313|EMBL:EEW51555.1};
GN ORFNames=HMPREF0520_1052 {ECO:0000313|EMBL:EEW51555.1};
OS Lactobacillus iners DSM 13335.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=525328 {ECO:0000313|EMBL:EEW51555.1, ECO:0000313|Proteomes:UP000004115};
RN [1] {ECO:0000313|EMBL:EEW51555.1, ECO:0000313|Proteomes:UP000004115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13335 {ECO:0000313|EMBL:EEW51555.1,
RC ECO:0000313|Proteomes:UP000004115};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEW51555.1}.
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DR EMBL; ACLN01000015; EEW51555.1; -; Genomic_DNA.
DR RefSeq; WP_006729096.1; NZ_GG700802.1.
DR AlphaFoldDB; C8PD82; -.
DR GeneID; 69785201; -.
DR PATRIC; fig|525328.13.peg.964; -.
DR HOGENOM; CLU_003433_0_0_9; -.
DR OrthoDB; 9808002at2; -.
DR Proteomes; UP000004115; Unassembled WGS sequence.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EEW51555.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000004115};
KW Transferase {ECO:0000313|EMBL:EEW51555.1}.
FT DOMAIN 5..368
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 381 AA; 41420 MW; 2919AA6916E8E7CC CRC64;
MKKNIYLDNA ATTPVSPSVA ARINDEMLDD FGNASSQHYF GRKARAAVEV ARNIIADSIN
AKANEIVFTS GGTESNNTAI YGTAKLRSHL GKKIITTKVE HPSVLNPMKD LESQGYNIVY
LDVDQTGHIS LEQLKDELTD DTILVSIMSV NNEVGSIMPI EEIGQLVKGT NALFHVDDVQ
GFGNIDIDVQ KSNIDLMSTS AHKINGPKFL GFLYEKEGIN LPPLLLGGEQ ELKRRPGTEN
VPAISGFGVA VKESNIDKKE QQKKYQNLQN IIINKLKHDH VDFEVNGSIS GSVSHHVLNL
WLKGIDTALA ITNLDLAGFA VSGGSACTAG SLHPSHVLAA MYGESSPRLR ESIRVSFSRF
TSEDDVTSFA AELADMCKRL V
//
