ID C8VYA6_DESAS Unreviewed; 773 AA.
AC C8VYA6;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ACV62787.1};
GN OrderedLocusNames=Dtox_1949 {ECO:0000313|EMBL:ACV62787.1};
OS Desulfofarcimen acetoxidans (strain ATCC 49208 / DSM 771 / KCTC 5769 / VKM
OS B-1644 / 5575) (Desulfotomaculum acetoxidans).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulfofarcimen.
OX NCBI_TaxID=485916 {ECO:0000313|EMBL:ACV62787.1, ECO:0000313|Proteomes:UP000002217};
RN [1] {ECO:0000313|EMBL:ACV62787.1, ECO:0000313|Proteomes:UP000002217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49208 / DSM 771 / VKM B-1644
RC {ECO:0000313|Proteomes:UP000002217};
RX PubMed=21304664; DOI=10.4056/sigs.39508;
RA Spring S., Lapidus A., Schroder M., Gleim D., Sims D., Meincke L.,
RA Glavina Del Rio T., Tice H., Copeland A., Cheng J.F., Lucas S., Chen F.,
RA Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Chain P., Saunders E., Brettin T., Detter J.C.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Han C.;
RT "Complete genome sequence of Desulfotomaculum acetoxidans type strain
RT (5575).";
RL Stand. Genomic Sci. 1:242-253(2009).
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DR EMBL; CP001720; ACV62787.1; -; Genomic_DNA.
DR RefSeq; WP_015757492.1; NC_013216.1.
DR AlphaFoldDB; C8VYA6; -.
DR STRING; 485916.Dtox_1949; -.
DR KEGG; dae:Dtox_1949; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2200; Bacteria.
DR HOGENOM; CLU_015702_2_0_9; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000002217; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000002217}.
FT DOMAIN 45..192
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 186..436
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT DOMAIN 458..517
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 615..766
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 773 AA; 87381 MW; FE5E639C9DA79AC4 CRC64;
MISVKNTYRV FKEILMSNTG NILLRQSAKQ KLLTEKFACH ISRGKIIGVM YLDIVRFHEV
QQIHGSIMVD RVLNLLEESL KKIITKFLPD DSVLAVENLW ADDFVILFTL SDKTSTEELS
NLAVALRLSL RDNLSFQFIK LLGSELELHI GYAIIEPAAD IKHDIKLYNA LREAQKVAKG
TLSLGTINLA KKFKELLSNH ELRSVYQPIV SLSSGEILGW EALTRGPENS YFSNPDVIFS
FAEEIELLCT TEMVCRETAI NNFGKLGPEQ KLFLNVNPRT MTDPNFVKGE TLKKLEEYGL
TPQNIVFEIT EQHSIKNYYL FKKTVEHYRN QGYQVAADDV GAGFSGLQSI AEIRPDFIKV
DMSLIRDIHI NPVKEAVVES LITLAEKINS QVIAEGIESQ NELNTLLSLG VHFGQGFYLA
RPAFPKQTVN KTLISYIKRQ KNKDLNGNWR QPLSIGDIAV PAVIIHEDTS VAEVKEKLDM
LSQPIGGVVV VRKERPIGLV MRHKLYRVLS SQYGVPLYWQ RPISVIMDCS PLQVENHITI
EQAAEIAMNR EQDKIYDDIV VVEKGKLTGV VTIQKMLDSI TKIQVELAKG ANPLTSLPGN
VAIELELSRR AGNGQNCIVI YADLDRFKSY NDTYGFERGD QMIKLTARIV SHATKKYGSR
NDFVGHIGGD DLIIITLPEY AEHICRSIVL LFERLKKRCF SPNDREQSEF YGQDRDGFQK
WLPLVSVSLA IVKCQDKKSY LTLAERAAQL KKYAKSLPGS VYVQDRCTDY KIQ
//
