ID C8VYU7_DESAS Unreviewed; 397 AA.
AC C8VYU7;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACV64818.1};
GN OrderedLocusNames=Dtox_4150 {ECO:0000313|EMBL:ACV64818.1};
OS Desulfofarcimen acetoxidans (strain ATCC 49208 / DSM 771 / KCTC 5769 / VKM
OS B-1644 / 5575) (Desulfotomaculum acetoxidans).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulfofarcimen.
OX NCBI_TaxID=485916 {ECO:0000313|EMBL:ACV64818.1, ECO:0000313|Proteomes:UP000002217};
RN [1] {ECO:0000313|EMBL:ACV64818.1, ECO:0000313|Proteomes:UP000002217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49208 / DSM 771 / VKM B-1644
RC {ECO:0000313|Proteomes:UP000002217};
RX PubMed=21304664; DOI=10.4056/sigs.39508;
RA Spring S., Lapidus A., Schroder M., Gleim D., Sims D., Meincke L.,
RA Glavina Del Rio T., Tice H., Copeland A., Cheng J.F., Lucas S., Chen F.,
RA Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Chain P., Saunders E., Brettin T., Detter J.C.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Han C.;
RT "Complete genome sequence of Desulfotomaculum acetoxidans type strain
RT (5575).";
RL Stand. Genomic Sci. 1:242-253(2009).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001720; ACV64818.1; -; Genomic_DNA.
DR RefSeq; WP_015759488.1; NC_013216.1.
DR AlphaFoldDB; C8VYU7; -.
DR STRING; 485916.Dtox_4150; -.
DR KEGG; dae:Dtox_4150; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_4_9; -.
DR OrthoDB; 9810430at2; -.
DR Proteomes; UP000002217; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002217};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..397
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038479214"
FT DOMAIN 60..313
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 94..147
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 397 AA; 42411 MW; 3856C26F1FF073FB CRC64;
MRKLVVIIAC LAVGLFILTG CQSTKSTANK NSAVSVNTAK AVRGQLDDST TVSGKLEALA
SADVVPKVAG KVNKIPVDIG SEVHAGDLLA ALDAPELLAA VQQAEANLEK ARQSDLITMK
NQAQSNLATT ETTLKNAEAD YNRAKALYEQ KAVSQQSFEQ TQKAYELAES AYNLAKQNLD
TIENGTIPNT IKVSEAALAQ ARANYSNMII TAPISGVITA KNVNIGEKTP TDKPLVSIVN
LNKVVVVTNI SENIVNKIKV GQKIPVLLQA VSDKPFQGEI TNISYAADTA TKAYPIKIQI
DNPEHKLKPG MFAEVKLEGN KESFLLVPRE AVLNTDKGSF VFTTDGQKLQ RKEIKTGRSD
GKNIAVISGL NEGEVIVASG VDSLQDGMKI VLQNKSK
//
