ID C8WI55_EGGLE Unreviewed; 537 AA.
AC C8WI55;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ACV55796.1};
GN OrderedLocusNames=Elen_1832 {ECO:0000313|EMBL:ACV55796.1};
OS Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 /
OS KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (Eubacterium lentum).
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Eggerthella.
OX NCBI_TaxID=479437 {ECO:0000313|EMBL:ACV55796.1, ECO:0000313|Proteomes:UP000001377};
RN [1] {ECO:0000313|EMBL:ACV55796.1, ECO:0000313|Proteomes:UP000001377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 /
RC NCTC 11813 / VPI 0255 / 1899 B {ECO:0000313|Proteomes:UP000001377};
RX PubMed=21304654; DOI=10.4056/sigs.33592;
RA Saunders E., Pukall R., Abt B., Lapidus A., Glavina Del Rio T.,
RA Copeland A., Tice H., Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D.,
RA Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Chain P., Meincke L., Sims D., Brettin T., Detter J.C.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Han C.;
RT "Complete genome sequence of Eggerthella lenta type strain (IPP VPI
RT 0255).";
RL Stand. Genomic Sci. 1:174-182(2009).
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DR EMBL; CP001726; ACV55796.1; -; Genomic_DNA.
DR AlphaFoldDB; C8WI55; -.
DR STRING; 479437.Elen_1832; -.
DR PaxDb; 479437-Elen_1832; -.
DR KEGG; ele:Elen_1832; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_11; -.
DR Proteomes; UP000001377; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ACV55796.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001377}.
FT DOMAIN 30..404
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 455..530
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 537 AA; 59653 MW; 4CFEF3C1D6B6C58F CRC64;
MEKVRRLTDI VGNETVRSLW DGLVAACGER EFLLFRDRTG STSTYTYRAF NEEIDRAANV
FLSMGVAAGE RVAVQLCTCP EFMMCLFGLA KIGAVMVPMN EQYLVEEAAF VLERTEASCA
VVEPKFLGLY RAVRDSGPYC PKGVLVARTH DDKVEGVEEA RAALERDGSL HDFSRLRAEA
AAELDEVRPL SADDPAEIIF TSGTTSRPKG VVLTHANILF SGLYGDWEVA LTKNDRLLTT
MPACHSNFQL AALMPVLTVG ATLIVVEKYS ASRFWSQIRE FKATVTQCVA MMLRTLMLQP
ASPDDRNHEL REILYFLPVS DAEKEAFEQR FGVSLMNTYG STESIGWVLT DPPTGARRWP
SVGRAGLGYE VRITREDGTQ ADPGEVGEIQ VRGVRGRTIM KEYFNDPEAT ARTFTEDGWL
KTGDKGYVDE DGWFFFVDRK VNMIKRAGEN ISTTELENVL AGHPRIAEAA VIGVPDPIRD
QAVKAFVLPA AGARITEEEV LAYCEEHMAG FKVPSYVEIV DSFPRTCSMK IEKKLLK
//
