ID C8XG08_NAKMY Unreviewed; 529 AA.
AC C8XG08;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Methylcrotonoyl-CoA carboxylase {ECO:0000313|EMBL:ACV78119.1};
DE EC=6.4.1.4 {ECO:0000313|EMBL:ACV78119.1};
GN OrderedLocusNames=Namu_1729 {ECO:0000313|EMBL:ACV78119.1};
OS Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / CIP 104796 / JCM
OS 9543 / NBRC 105858 / Y-104) (Microsphaera multipartita).
OC Bacteria; Actinomycetota; Actinomycetes; Nakamurellales; Nakamurellaceae;
OC Nakamurella.
OX NCBI_TaxID=479431 {ECO:0000313|EMBL:ACV78119.1, ECO:0000313|Proteomes:UP000002218};
RN [1] {ECO:0000313|Proteomes:UP000002218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 /
RC Y-104 {ECO:0000313|Proteomes:UP000002218};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Ovchinnikova G., Sims D., Meincke L., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Nakamurella multipartita DSM 44233.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACV78119.1, ECO:0000313|Proteomes:UP000002218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 /
RC Y-104 {ECO:0000313|Proteomes:UP000002218};
RX PubMed=21304699;
RA Tice H., Mayilraj S., Sims D., Lapidus A., Nolan M., Lucas S.,
RA Glavina Del Rio T., Copeland A., Cheng J.F., Meincke L., Bruce D.,
RA Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Detter J.C., Brettin T., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Chen F.;
RT "Complete genome sequence of Nakamurella multipartita type strain (Y-
RT 104).";
RL Stand. Genomic Sci. 2:168-175(2010).
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DR EMBL; CP001737; ACV78119.1; -; Genomic_DNA.
DR AlphaFoldDB; C8XG08; -.
DR STRING; 479431.Namu_1729; -.
DR KEGG; nml:Namu_1729; -.
DR eggNOG; COG4799; Bacteria.
DR HOGENOM; CLU_018822_0_1_11; -.
DR InParanoid; C8XG08; -.
DR OrthoDB; 9803706at2; -.
DR Proteomes; UP000002218; Chromosome.
DR GO; GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR InterPro; IPR045190; MCCB/AccD1-like.
DR PANTHER; PTHR22855; ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR22855:SF13; METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ACV78119.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002218}.
FT DOMAIN 24..279
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 280..521
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 56399 MW; A695B501ACCE950E CRC64;
MTGAMTDTPT PTADGGPAPV ASLPELVDEL RTRLAVVRQG GSEAARRKHT DRGKLLARDR
VDRLLDPGSP FLELGALAAY EMYGGAVPSA GIVTGIGRVS GREVVVVAND ATVKGGTYYP
MTVKKHLRAQ TVAGENHLPC IYLVDSGGAF LPMQDEVFPD REHFGRIFYN QATLSARGIP
QIASVMGSCT AGGAYMPAMS DETVIVRNQG TIFLGGPPLV KAATGEIVTA EDLGGGDVHA
RISGVVDHLA QDDAHALAIV RSIVGTLHRP VVTPAYDLAP VEEPHEDPAS LHDVVPADTR
TPYDVREVIR RIVDGSRLHE FKKLYGQTLV CGFAHIWGHP VGIVANNGIL FSESSLKGAH
FIELCNQRGI PLVFLQNITG FMVGRQYENG GIAKDGAKLV TAVACSVVPK FTVVIGGSFG
AGNYGMCGRA YDPRFLWMWP NARISVMGGE QAASVLATVR GFDDPQEEEA FKAPIRAQYE
QQGSPYYSTA RLWDDGIIDP ADTRRVLGLG LAAAANAPTP APSYGVFRM
//
