ID C9A7B0_ENTCA Unreviewed; 940 AA.
AC C9A7B0;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN ORFNames=ECBG_00640 {ECO:0000313|EMBL:EEV38371.2};
OS Enterococcus casseliflavus EC20.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=565655 {ECO:0000313|EMBL:EEV38371.2, ECO:0000313|Proteomes:UP000012675};
RN [1] {ECO:0000313|EMBL:EEV38371.2, ECO:0000313|Proteomes:UP000012675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC20 {ECO:0000313|EMBL:EEV38371.2,
RC ECO:0000313|Proteomes:UP000012675};
RG The Broad Institute Genome Sequencing Platform;
RA Feldgarden M., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Gilmore M., Manson J., Palmer K., Carniol K.,
RA Lander E., Nusbaum C., Galagan J., Birren B.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEV38371.2, ECO:0000313|Proteomes:UP000012675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC20 {ECO:0000313|EMBL:EEV38371.2,
RC ECO:0000313|Proteomes:UP000012675};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Russ C., Feldgarden M., Gilmore M., Manson J., Palmer K., Carniol K.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus casseliflavus EC20 (899205).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP004856; EEV38371.2; -; Genomic_DNA.
DR AlphaFoldDB; C9A7B0; -.
DR KEGG; ecas:ECBG_00640; -.
DR eggNOG; COG1221; Bacteria.
DR eggNOG; COG3933; Bacteria.
DR HOGENOM; CLU_014204_1_1_9; -.
DR Proteomes; UP000012675; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.510; Phosphotransferase system, mannose-type IIA component; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR004701; PTS_EIIA_man-typ.
DR InterPro; IPR036662; PTS_EIIA_man-typ_sf.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF90; TRANSCRIPTIONAL REGULATORY PROTEIN LEVR; 1.
DR Pfam; PF03610; EIIA-man; 1.
DR Pfam; PF00874; PRD; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53062; PTS system fructose IIA component-like; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51372; PRD_2; 1.
DR PROSITE; PS51096; PTS_EIIA_TYPE_4; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000012675};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 110..344
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT DOMAIN 467..573
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 574..701
FT /note="PTS EIIA type-4"
FT /evidence="ECO:0000259|PROSITE:PS51096"
SQ SEQUENCE 940 AA; 105778 MW; EA0DDA5EA088C30C CRC64;
MGKRIERIYQ YIVENTMSGL GEKKGLSTSE VADHLAIQRS NASKDLNKLV KEGRVEKSDS
RPVRYWAADV DPSSREKYVP SYKESRPQRE KAFPQRVQGK PSDRDIFATI IGANGSMKNA
VEQAKAAILY PPKGLNCLIT GPTGSGKTYF AHAMFQFAKS NQVIADDKEL IVFNCADYAN
NPELLMSHLF GYVRGAFTGA DQEKIGIIDQ ADESMLFLDE IHRLPPEGQE MIFYFMDHGT
FSRLGETGKN HQANVRIVGA TTEDPNSTLL DTFTRRIPIN IQLPFFEKRP ASEKVDLVRV
LVGQEASRIQ RTITLTEDVV KALIGSVSFG NIGQLKSNVQ LVCARGFLNH MQQDEIEIDL
IDLPEGIRSG LIVLGNRRNE LAELSKILEP KISIQPNQNL NNIQSDSYEL PYNLYDIIGD
KAALLKADGL DQEAINHFIS TDINVHLKSF YKDHGFSFNS VNKLSEFVDQ KVISVTNQIY
EMVRKRLNYD FQQNFIYAMS LHISSFLKKI HLGEERQTND NIRQMVADYP QEFEVAKEVR
NFIGDSFHVA IPESESYYLA VLLVSLRTTH SSGKIGVVVA AHGNSTASSM VQVVKQLLEV
DQVTAVDMPL DMPPAVALKK IVDSVRAVND GSGVILLVDM GSLATFNNEI QRETGVAVRT
VDMVTTSIVL ETVRKASVIG TDLDQLYDSL RKFRGYGAVT VEEPVTQNHH PKAILAVCAS
GKGTAQRIKE LIQSSLSKRQ NQNVDVVTLS VADLRTDLDQ IQQRYRLIAA TGIIDPHIDA
PFISLERFID QDVDLLLDDI LLENDLSFED EVQLDDRQAK EICVRYLEEN FTYINAKKVV
EPLWKFGEEI IHDLDLVGAQ QGFQINFVMH GAGMLERILL RQPLTVSEID LAAMEENPLY
GQLHVHVQSF SRLMNIEVTK TEEYYLLELI KNHHEKEMYF
//
