ID C9IY79_HUMAN Unreviewed; 141 AA.
AC C9IY79;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Phospholipase D1 {ECO:0000313|Ensembl:ENSP00000400639.1};
DE Flags: Fragment;
GN Name=PLD1 {ECO:0000313|Ensembl:ENSP00000400639.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000400639.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000400639.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0007829|PubMed:18669648}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN [3] {ECO:0000313|Ensembl:ENSP00000400639.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC008134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC078953; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9IY79; -.
DR SMR; C9IY79; -.
DR MassIVE; C9IY79; -.
DR PeptideAtlas; C9IY79; -.
DR ProteomicsDB; 7629; -.
DR Antibodypedia; 3866; 333 antibodies from 40 providers.
DR Ensembl; ENST00000418087.1; ENSP00000400639.1; ENSG00000075651.17.
DR UCSC; uc062pys.1; human.
DR HGNC; HGNC:9067; PLD1.
DR VEuPathDB; HostDB:ENSG00000075651; -.
DR GeneTree; ENSGT00940000155015; -.
DR HOGENOM; CLU_1986653_0_0_1; -.
DR OMA; EWRLDQI; -.
DR ChiTaRS; PLD1; human.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000075651; Expressed in gall bladder and 178 other cell types or tissues.
DR ExpressionAtlas; C9IY79; baseline and differential.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR Pfam; PF00787; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:C9IY79,
KW ECO:0007829|MaxQB:C9IY79};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 81..141
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT NON_TER 141
FT /evidence="ECO:0000313|Ensembl:ENSP00000400639.1"
SQ SEQUENCE 141 AA; 16525 MW; 7C9D5EEF3BEFE369 CRC64;
MSLKNEPRVN TSALQKIAAD MSNIIENLDT RELHFEGEEV DYDVSPSDPK IQEVYIPFSA
IYNTQGFKEP NIQTYLSGCP IKAQVLEVER FTSTTRVPSI NLYTIELTHG EFKWQVKRKF
KHFQEFHREL LKYKAFIRIP I
//
