ID C9JLU5_HUMAN Unreviewed; 55 AA.
AC C9JLU5;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=MBL associated serine protease 1 {ECO:0000313|Ensembl:ENSP00000409047.1};
DE Flags: Fragment;
GN Name=MASP1 {ECO:0000313|Ensembl:ENSP00000409047.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000409047.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000409047.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000409047.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; AC007920; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF457720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9JLU5; -.
DR SMR; C9JLU5; -.
DR MassIVE; C9JLU5; -.
DR PeptideAtlas; C9JLU5; -.
DR Antibodypedia; 889; 410 antibodies from 28 providers.
DR Ensembl; ENST00000425937.1; ENSP00000409047.1; ENSG00000127241.18.
DR UCSC; uc062rgz.1; human.
DR HGNC; HGNC:6901; MASP1.
DR VEuPathDB; HostDB:ENSG00000127241; -.
DR GeneTree; ENSGT00950000183084; -.
DR HOGENOM; CLU_3037639_0_0_1; -.
DR OMA; QHWVAQG; -.
DR ChiTaRS; MASP1; human.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000127241; Expressed in endocervix and 136 other cell types or tissues.
DR ExpressionAtlas; C9JLU5; baseline and differential.
DR CDD; cd00041; CUB; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24255; COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED; 1.
DR PANTHER; PTHR24255:SF13; MANNAN-BINDING LECTIN SERINE PROTEASE 1; 1.
DR Pfam; PF00431; CUB; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Proteomics identification {ECO:0007829|PeptideAtlas:C9JLU5};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 1..55
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT NON_TER 55
FT /evidence="ECO:0000313|Ensembl:ENSP00000409047.1"
SQ SEQUENCE 55 AA; 6508 MW; A7B2F9F91CAAE3AD CRC64;
MFGQIQSPGY PDSYPSDSEV TWNITVPDGF RIKLYFMHFN LESSYLCEYD YVKVE
//
