ID C9L858_BLAHA Unreviewed; 254 AA.
AC C9L858;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=TipAS antibiotic-recognition domain protein {ECO:0000313|EMBL:EEX21550.1};
GN ORFNames=BLAHAN_05577 {ECO:0000313|EMBL:EEX21550.1};
OS Blautia hansenii DSM 20583.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=537007 {ECO:0000313|EMBL:EEX21550.1, ECO:0000313|Proteomes:UP000003755};
RN [1] {ECO:0000313|EMBL:EEX21550.1, ECO:0000313|Proteomes:UP000003755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20583 {ECO:0000313|EMBL:EEX21550.1,
RC ECO:0000313|Proteomes:UP000003755};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEX21550.1}.
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DR EMBL; ABYU02000017; EEX21550.1; -; Genomic_DNA.
DR RefSeq; WP_003020960.1; NZ_GG698589.1.
DR AlphaFoldDB; C9L858; -.
DR STRING; 537007.BLAHAN_05577; -.
DR KEGG; bhan:CGC63_08885; -.
DR eggNOG; COG0789; Bacteria.
DR HOGENOM; CLU_060077_0_3_9; -.
DR Proteomes; UP000003755; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01106; HTH_TipAL-Mta; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 1.10.490.50; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR PANTHER; PTHR30204:SF90; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF89082; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..71
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 254 AA; 29910 MW; 6DCC734E3F3AC5AC CRC64;
MEYSIRQLAD LTGVSTRTLR YYDERGLLKP SRVNEQGCRY YEQEQVDLLQ QILFYRERNL
GLDVIKEIIS NPQFDAAQAL EEHLIALMEQ EKHISTLIQT VKNTIADMKG EERNMSDKEK
FEGFKRELIE EKERLYGKEA REKYGEEAVD EANQKIMGLS EADYERFKNL EKEVLRQLEE
AVRNKELPES ETGHRIVLLH KDWLGYTWKE YSAQAHKGLA SMYIADERFL AYYDKNIKGC
GEFLVKAVDY WAGR
//
