ID C9REP5_METVM Unreviewed; 381 AA.
AC C9REP5;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=RNA methylase {ECO:0000313|EMBL:ACX72047.1};
GN OrderedLocusNames=Metvu_0180 {ECO:0000313|EMBL:ACX72047.1};
OS Methanocaldococcus vulcanius (strain ATCC 700851 / DSM 12094 / M7)
OS (Methanococcus vulcanius).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=579137 {ECO:0000313|EMBL:ACX72047.1, ECO:0000313|Proteomes:UP000002063};
RN [1] {ECO:0000313|EMBL:ACX72047.1, ECO:0000313|Proteomes:UP000002063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700851 / DSM 12094 / M7
RC {ECO:0000313|Proteomes:UP000002063};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Lcollab F.I., Brettin T., Detter J.C.,
RA Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Ovchinikova G., Sieprawska-Lupa M., Whitman W.B., Woyke T.;
RT "Complete sequence of chromosome of Methanocaldococcus vulcanius M7.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001787; ACX72047.1; -; Genomic_DNA.
DR RefSeq; WP_012819593.1; NC_013407.1.
DR AlphaFoldDB; C9REP5; -.
DR STRING; 579137.Metvu_0180; -.
DR GeneID; 8512508; -.
DR KEGG; mvu:Metvu_0180; -.
DR eggNOG; arCOG00048; Archaea.
DR HOGENOM; CLU_032119_0_0_2; -.
DR OrthoDB; 7080at2157; -.
DR Proteomes; UP000002063; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR NCBIfam; NF040721; Trm14_Arch; 1.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ACX72047.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000313|EMBL:ACX72047.1}.
FT DOMAIN 43..157
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 381 AA; 43516 MW; 8A1D0027CDE94A64 CRC64;
MDYYSTLSPG LEKVSQREIE TLGGKIREIR NNKGRIFFKG DLEVIPKINY LSRTIERLNI
LLHREEIPNI SLEDIYERVY SIDWSEWIKE DQAFAIRPLR VGTHNFTSID IGRVAGEALI
NSYKRDKNVR LKVNLNEPDI IVRVEVIFDE VIVGLDTTGD IALDKRGYRV FNHPAHLNAT
IASSLIYLSD WKDEETLLDP MCGSGTIPIE GALIKRNIPP GKFREKKYGF KFVNIFGYGL
LEEIKKSILE NEELYSIYGI DKNEKYILGA VENARSAGVF DTISLSIGDA TKMEENFKDI
DVIIANPPYG IRMGSKRGVK KLYEKFLLSA KKIMHDSSRM VVITAEDKLF REAVVRQNFN
IMDEFAVMFG GLLTKVFIIS L
//
