ID   C9SC82_VERA1            Unreviewed;       706 AA.
AC   C9SC82;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=Homeobox and C2H2 transcription factor {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VDBG_02075 {ECO:0000313|EMBL:EEY15966.1};
OS   Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)
OS   (Verticillium wilt of alfalfa) (Verticillium albo-atrum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=526221 {ECO:0000313|Proteomes:UP000008698};
RN   [1] {ECO:0000313|Proteomes:UP000008698}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136
RC   {ECO:0000313|Proteomes:UP000008698};
RX   PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA   Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA   Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA   Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA   Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA   Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA   Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT   "Comparative genomics yields insights into niche adaptation of plant
RT   vascular wilt pathogens.";
RL   PLoS Pathog. 7:E1002137-E1002137(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
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DR   EMBL; DS985215; EEY15966.1; -; Genomic_DNA.
DR   RefSeq; XP_003007887.1; XM_003007841.1.
DR   AlphaFoldDB; C9SC82; -.
DR   GeneID; 9535840; -.
DR   KEGG; val:VDBG_02075; -.
DR   eggNOG; KOG0773; Eukaryota.
DR   HOGENOM; CLU_008497_2_1_1; -.
DR   OMA; NQARWIM; -.
DR   OrthoDB; 450547at2759; -.
DR   Proteomes; UP000008698; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000008698};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          16..79
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          228..256
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DNA_BIND        18..80
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          162..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..195
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   706 AA;  79801 MW;  7F7061968B85F3D8 CRC64;
     MSAVVANGPA ELEISSVPAK VGTRFSTRAL RVLRNWFAAH EDHPYPRAGD MESLQAQTGL
     NKLQVSTWLA NTRRRTKSRV PVRPTSPSVL SAPNLEAMEI PTSRRPELVD QMDPLGRWQN
     SPPEDEAADA KAILKAISAS PDASAQPRHP LLVRPQPSVW GEWSSASSAG TSQSSNSSGG
     SAYSQGSASS RAQSRDLARY TKHKRRRNRG TAQSATTRTK LSQLPRKFQC TFCTESFAQK
     HGWQRHEKTM HLSLERWECS PEGPYSRDDD GHQACAYCSR REPDEGHMLA HNFEVCIDRP
     PEERSFYRRD HLIQHLKAVH HVKLDPSLME RWKQTIQDIK SSCGFCGLSM TSWTERADHL
     ADHFKSGATM AQWLGDWGFD DDVVQMVQNS IPPYLIEFER TSPWPFTTDR GPPATPANAF
     ELIKIELDYF ASCLDEKNLP PSQEVLQYES CCIIVGSEML SPSQDAHNTP RSWLRDLLMS
     DEHVARRARN TPLASIVKDR ATELRINSKA DIFDSCSLEE QLQLFMVQNL AYESPVDDVD
     LQRGACQVVQ NADAQSREPS ELFMSFLTGL INNSSHWLAP FRQRSEATAL RASRDIRLGE
     PGFDASHHRE LQDQKDQSGN AALGTLTEPV FALDEPFDQE LPRQELLAEL PGPQRFTFLS
     TDTFYWGLRR ELSRFVAMSM SPRNPDCHIP TDEELQNQAR WIMFDR
//