ID   C9SCD7_VERA1            Unreviewed;       636 AA.
AC   C9SCD7;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Rho guanine nucleotide exchange factor scd1 {ECO:0000313|EMBL:EEY16752.1};
GN   ORFNames=VDBG_02861 {ECO:0000313|EMBL:EEY16752.1};
OS   Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)
OS   (Verticillium wilt of alfalfa) (Verticillium albo-atrum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=526221 {ECO:0000313|Proteomes:UP000008698};
RN   [1] {ECO:0000313|Proteomes:UP000008698}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136
RC   {ECO:0000313|Proteomes:UP000008698};
RX   PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA   Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA   Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA   Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA   Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA   Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA   Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT   "Comparative genomics yields insights into niche adaptation of plant
RT   vascular wilt pathogens.";
RL   PLoS Pathog. 7:E1002137-E1002137(2011).
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DR   EMBL; DS985216; EEY16752.1; -; Genomic_DNA.
DR   RefSeq; XP_003006722.1; XM_003006676.1.
DR   AlphaFoldDB; C9SCD7; -.
DR   STRING; 526221.C9SCD7; -.
DR   GeneID; 9532864; -.
DR   KEGG; val:VDBG_02861; -.
DR   eggNOG; KOG3519; Eukaryota.
DR   HOGENOM; CLU_007879_1_0_1; -.
DR   OMA; CCKEASP; -.
DR   OrthoDB; 23973at2759; -.
DR   Proteomes; UP000008698; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd00014; CH_SF; 1.
DR   CDD; cd13246; PH_Scd1; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR010481; Cdc24/Scd1_N.
DR   InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR001331; GDS_CDC24_CS.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR   PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR   Pfam; PF06395; CDC24; 1.
DR   Pfam; PF15411; PH_10; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS00741; DH_1; 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008698}.
FT   DOMAIN          219..393
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   REGION          437..463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          557..636
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        437..461
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..617
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   636 AA;  70253 MW;  954D24C4D655C7CA CRC64;
     MAHAPLLRTN TAPVFSQSSN GVGGISTMSH APRASQLSGS TAYNSSSVSL ASLSSAATAA
     TTATATPQNG GPVIATANII NQKADASRSL YHLCMALKVR LAQVPDFGPY LQQLDPYDPV
     ESLWGLFRTG FPLLEIYNAL QPPVPLKIDD SAPKTTTADK KAKIAVFKFI QACLKDLGIP
     SADCFVINDV LGNDTTGFVK VTPDPEDEAA PEPGSKLSYR DYIVKELVDT ERKYVQDLEN
     LHDLKSSLET KGIITGDTIH QIFLNINAIL DFQRRFLIRV ETTNSMPQSS QHWGAPFVVY
     EEAFDIYRPF IANQRKAAQV ANQVFEQIKT AAHPVAVDFN TLDGFLLKPM QRLVKYPLLL
     KDLKKKTEDE TAQSELAAGI EAAERVLTKA NEEVNRDLLD EALEELRVRV DDWKSHKIEQ
     FGKLLRHGVY TVVTGKTDQE KEEISPNKSK DKKDKTRSTG PRIRNKNAKL QLKGRIFMTN
     VTDVVSLSKP GSYSVQIWWK GDPGVENFMI KFNNEEMLKK WALGLETQRK VWSQKTAGSP
     DQAAPEFAWT QAHGSKLENP YLNQGDDEDD EDLGPTSAPP QFPMSQQTSG NGPRLPRNAS
     STSLRQRSAT NDSTGSLAGM VPPLPHASRY LSPRDR
//