ID   C9ZLG6_TRYB9            Unreviewed;       278 AA.
AC   C9ZLG6;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   13-SEP-2023, entry version 28.
DE   RecName: Full=VIT family {ECO:0008006|Google:ProtNLM};
GN   ORFNames=TbgDal_III5170 {ECO:0000313|EMBL:CBH10175.1};
OS   Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=679716 {ECO:0000313|EMBL:CBH10175.1, ECO:0000313|Proteomes:UP000002316};
RN   [1] {ECO:0000313|Proteomes:UP000002316}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHOM/CI/86/DAL972 {ECO:0000313|Proteomes:UP000002316};
RX   PubMed=20404998; DOI=10.1371/journal.pntd.0000658;
RA   Jackson A.P., Sanders M., Berry A., McQuillan J., Aslett M.A., Quail M.A.,
RA   Chukualim B., Capewell P., MacLeod A., Melville S.E., Gibson W.,
RA   Barry J.D., Berriman M., Hertz-Fowler C.;
RT   "The genome sequence of Trypanosoma brucei gambiense, causative agent of
RT   chronic human african trypanosomiasis.";
RL   PLoS Negl. Trop. Dis. 4:E658-E658(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CCC1 family.
CC       {ECO:0000256|ARBA:ARBA00007049}.
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DR   EMBL; FN554966; CBH10175.1; -; Genomic_DNA.
DR   RefSeq; XP_011772465.1; XM_011774163.1.
DR   AlphaFoldDB; C9ZLG6; -.
DR   GeneID; 23859323; -.
DR   KEGG; tbg:TbgDal_III5170; -.
DR   VEuPathDB; TriTrypDB:Tbg972.3.5170; -.
DR   OrthoDB; 149595at2759; -.
DR   Proteomes; UP000002316; Chromosome 3.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR   CDD; cd02437; CCC1_like_1; 1.
DR   InterPro; IPR008217; Ccc1_fam.
DR   Pfam; PF01988; VIT1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        48..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        220..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   278 AA;  30379 MW;  69DA7793722D4A1B CRC64;
     MDSFRLTEKD EARCSFGDPK RSRDAHDNRM EHFNVDIRKN SALRNRSLVC GCLTGFTCAA
     GAIGALAGMY RSSLGSTSQD KRFAPLLIAH AFSGGVGIAF TVCRSLLFER AVYEVELQRE
     LWEIDNHIAG EIQEMVAIYR AQGLLEEEAH MITRIFAKHR EAFANLMMVE ELGYSRLEPP
     AGWEAVVDAA IPSSIGYTLG WVLPLLPFMG SELSSARSEL VALCTLAAGI FVVSVGQSEV
     FFGSYANVWK AVGATVWNLS AAGLTYGATR FMACRSGV
//