ID C9ZVF2_TRYB9 Unreviewed; 969 AA.
AC C9ZVF2;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Protein transport protein sec23, putative {ECO:0000313|EMBL:CBH13390.1};
GN ORFNames=TbgDal_VIII3380 {ECO:0000313|EMBL:CBH13390.1};
OS Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=679716 {ECO:0000313|EMBL:CBH13390.1, ECO:0000313|Proteomes:UP000002316};
RN [1] {ECO:0000313|Proteomes:UP000002316}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/CI/86/DAL972 {ECO:0000313|Proteomes:UP000002316};
RX PubMed=20404998; DOI=10.1371/journal.pntd.0000658;
RA Jackson A.P., Sanders M., Berry A., McQuillan J., Aslett M.A., Quail M.A.,
RA Chukualim B., Capewell P., MacLeod A., Melville S.E., Gibson W.,
RA Barry J.D., Berriman M., Hertz-Fowler C.;
RT "The genome sequence of Trypanosoma brucei gambiense, causative agent of
RT chronic human african trypanosomiasis.";
RL PLoS Negl. Trop. Dis. 4:E658-E658(2010).
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DR EMBL; FN554971; CBH13390.1; -; Genomic_DNA.
DR RefSeq; XP_011775667.1; XM_011777365.1.
DR AlphaFoldDB; C9ZVF2; -.
DR GeneID; 23863522; -.
DR KEGG; tbg:TbgDal_VIII3380; -.
DR VEuPathDB; TriTrypDB:Tbg972.8.3380; -.
DR OrthoDB; 167360at2759; -.
DR Proteomes; UP000002316; Chromosome 8.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 2.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR037364; Sec23.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR11141; PROTEIN TRANSPORT PROTEIN SEC23; 1.
DR PANTHER; PTHR11141:SF22; PROTEIN TRANSPORT PROTEIN SEC23; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 4: Predicted;
FT DOMAIN 279..545
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 579..689
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 714..814
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 830..915
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 120..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 969 AA; 106675 MW; CB19F7CB60234C57 CRC64;
MQGHVPQQSY GGYPRQADYQ GLYPTQDVKQ GYVSYQDPAT LMEGHNAQYG GGTAEGTYSN
QYTQLQHQMN NYNYNANQTP WQQQYAPQQG IHNPANTNDT NMFAPPTAVG AAAAPHVGGA
VAPTGSGASA TTASHVPPPP PAAECTDENG LRWTWSTYPN HTRDGKQEAP SAAALTLPEM
VIPLACMYTP LFPIDASRMV IGDPTACGQQ CQNCGAFWSH HCYREEGKFW VCFSCQRRNQ
LPPHYRPEHP ALHNDTVEYI LPLEQPTTAQ ATRGVGFSPT FVFIIDTCIA VEELEALKCN
IQRCLNWLPP QSLIGLVSFG ARVSVWDLSG SSLSRCYSIR GDRAYTTAEL GNMLQLNDGL
PARGRFLVPL EECEFTLTTS IEGLQCHDGV TPVNKRPLRA TGTAVSAAVR LLEALPEVPV
KKEMSGAAPA GVAPVRKAGR VLLFTGGPCT RGPGTVVSIE KESMMRFHRD IIEGETPYYE
AAFKFYNEIQ LRLLDVNASL SVFAESFDQI GILEMRQAVD QTGGTFICGD TFDHQMFTIS
LQRYFDLCDL RPPGVESSGI SSAGDIDGSA PGALVANSGF GVKLHVHTSD DTLVSGVLGP
CVAAEKTSGT KAHRASISPI EIGVGGTTDW RVSTIDQGTT YTVVFDTATL NKVDGMPQQQ
QNRFIQFVTH FTTPLGESRI RVTSVALPIA PVTITADGVS TANPQYFSEY DTFDQTCAAT
VLARMTVSIL EKHPSKWNDA KRWLDTVLVR FVRRYGSFTP GSPESLRLRP CFTLFPSFVF
NLRRSEYFMV LNISPDESTF KRHWLMRESV DNCVLMIQPT LHSYDMETPT ATAVPLDSCS
LRPDNILLMD AFFNIHIMWG TVIFAWIQAR YQDNPEYAHF AQLLETVENE ATMLLDMRYP
YPRFSRTDAN GSEARHIKTR MNPTTTHHSG ARGGNGVADL SDVIYTDDAS IVKFMESLKQ
AVVTPESKK
//
