ID CAH11_PIG Reviewed; 331 AA.
AC Q866X6;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 08-NOV-2023, entry version 79.
DE RecName: Full=Carbonic anhydrase-related protein 11;
DE AltName: Full=CA-RP XI;
DE Short=CA-XI;
DE Short=CARP XI;
DE Flags: Precursor;
GN Name=CA11;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Chen Y., Huang C.-H.;
RT "Molecular identification of carbonic anhydrases (CA) and CA-related (CAR)
RT genes.";
RL Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Does not have a catalytic activity.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000305}.
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DR EMBL; AY075024; AAL78172.1; -; mRNA.
DR RefSeq; NP_001004038.1; NM_001004038.1.
DR AlphaFoldDB; Q866X6; -.
DR SMR; Q866X6; -.
DR STRING; 9823.ENSSSCP00000003409; -.
DR GlyCosmos; Q866X6; 4 sites, No reported glycans.
DR PaxDb; 9823-ENSSSCP00000003409; -.
DR GeneID; 445526; -.
DR KEGG; ssc:445526; -.
DR CTD; 770; -.
DR eggNOG; KOG0382; Eukaryota.
DR InParanoid; Q866X6; -.
DR OrthoDB; 49814at2759; -.
DR Proteomes; UP000008227; Unplaced.
DR Proteomes; UP000314985; Unplaced.
DR Proteomes; UP000694570; Unplaced.
DR Proteomes; UP000694571; Unplaced.
DR Proteomes; UP000694720; Unplaced.
DR Proteomes; UP000694722; Unplaced.
DR Proteomes; UP000694723; Unplaced.
DR Proteomes; UP000694724; Unplaced.
DR Proteomes; UP000694725; Unplaced.
DR Proteomes; UP000694726; Unplaced.
DR Proteomes; UP000694727; Unplaced.
DR Proteomes; UP000694728; Unplaced.
DR GO; GO:0016323; C:basolateral plasma membrane; IBA:GO_Central.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016836; F:hydro-lyase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IBA:GO_Central.
DR CDD; cd03121; alpha_CARP_X_XI_like; 1.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR041878; Alpha_CARP_X/XI.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF93; CARBONIC ANHYDRASE-RELATED PROTEIN 11; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..331
FT /note="Carbonic anhydrase-related protein 11"
FT /id="PRO_0000262535"
FT DOMAIN 33..306
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01134"
FT REGION 303..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 118
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 170
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 189
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 263
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 331 AA; 36395 MW; A1E8497B135D2088 CRC64;
MGGAARLSAP RALVLWAVLG AAAHIGPAPD PEDWWSYKDN LQGNFVPGPP FWGLVNAAWS
LCAVGKRQSP VDVELKRVLY DPFLPPLRLS TGGEKLRGTL YNTGRHVSFL PAPRPVVNVS
GGPLLYSHRL SELLLLFGAH DGAGSEHQIN HQGFSAEVQL IHFNQELYGN LSAASRGPNG
LAILSLFVNV SQVAGNSNPF LSRLLNRDTI TRISYKNDAY FLQDLSLELL FPESFGFITY
QGSLSTPPCS ETVTWILIDR ALNITSLQMH SLRLLSQNPP SQIFQSLSGN GRPLQPLAHR
ALRGNRDPRH PERRCRGPNY RLHVDGAPHG R
//
