ID   CPCE_MICDP              Reviewed;         294 AA.
AC   P07126; P05520;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   RecName: Full=Phycocyanobilin lyase subunit alpha;
DE            EC=4.-.-.-;
DE   AltName: Full=Phycocyanin operon protein CpcE;
GN   Name=cpcE;
OS   Microchaete diplosiphon (Fremyella diplosiphon).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Rivulariaceae;
OC   Microchaete.
OX   NCBI_TaxID=1197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Mazel D., Houmard J., Tandeau de Marsac N.;
RT   "A multigene family in Calothrix sp. PCC 7601 encodes phycocyanin, the
RT   major component of the cyanobacterial light harvesting antenna.";
RL   Mol. Gen. Genet. 211:296-304(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3127591; DOI=10.1016/0022-2836(88)90617-1;
RA   Conley P.B., Lemaux P.G., Grossman A.;
RT   "Molecular characterization and evolution of sequences encoding light-
RT   harvesting components in the chromatically adapting cyanobacterium
RT   Fremyella diplosiphon.";
RL   J. Mol. Biol. 199:447-465(1988).
CC   -!- FUNCTION: Required for the chromophorylation of the CpcA gene product.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: CpcE and CpcF associate to form a lyase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CpcE/RpcE/PecE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA30066.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X06084; CAA29466.1; -; Genomic_DNA.
DR   EMBL; X07013; CAA30066.1; ALT_INIT; Genomic_DNA.
DR   PIR; S00715; S00715.
DR   AlphaFoldDB; P07126; -.
DR   SMR; P07126; -.
DR   GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR004155; PBS_lyase_HEAT.
DR   PANTHER; PTHR12697; PBS LYASE HEAT-LIKE PROTEIN; 1.
DR   PANTHER; PTHR12697:SF38; PHYCOCYANOBILIN LYASE SUBUNIT ALPHA; 1.
DR   Pfam; PF13646; HEAT_2; 2.
DR   Pfam; PF03130; HEAT_PBS; 1.
DR   SMART; SM00567; EZ_HEAT; 6.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Antenna complex; Lyase; Phycobilisome.
FT   CHAIN           1..294
FT                   /note="Phycocyanobilin lyase subunit alpha"
FT                   /id="PRO_0000199267"
FT   CONFLICT        66..68
FT                   /note="IDV -> NDL (in Ref. 2; CAA30066)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        81
FT                   /note="N -> I (in Ref. 2; CAA30066)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        205..217
FT                   /note="SESTAGYNQYGDR -> QNHCRLQSVWRS (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   294 AA;  32269 MW;  95304C5FBE4C5B0A CRC64;
     MYRHLSEGIE DHREQEQKVE NAANIQDDNQ LTVEQAIANL QGEDLGLRVY AAWWLGRFRV
     DAPEAIDVLI QALEDEDDRT NVGGYPLRRN AARALGKLGE KRAVPALIKA LECSDFYVRE
     AAAQSLEMLG DSSSIPRLIE LLNDQVPGTL PAPEPPQLTQ PFDAIIEALG TLGASDAIPI
     IQEFLEHTVP RIQYAAARAM YQLTSESTAG YNQYGDRLVQ ALAQDDLQLR RAVLSDLGAI
     GYLPAAEAIA DTLAENSLKL ISLKGLLEKQ FQPTKPEDLS PGAIKVMQLM DALL
//