ID   D0A5H3_TRYB9            Unreviewed;       382 AA.
AC   D0A5H3;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=GTPase Era, mitochondrial {ECO:0000256|ARBA:ARBA00019149};
DE   AltName: Full=ERA-like protein 1 {ECO:0000256|ARBA:ARBA00030975};
GN   ORFNames=TbgDal_XI390 {ECO:0000313|EMBL:CBH16924.1};
OS   Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=679716 {ECO:0000313|EMBL:CBH16924.1, ECO:0000313|Proteomes:UP000002316};
RN   [1] {ECO:0000313|Proteomes:UP000002316}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHOM/CI/86/DAL972 {ECO:0000313|Proteomes:UP000002316};
RX   PubMed=20404998; DOI=10.1371/journal.pntd.0000658;
RA   Jackson A.P., Sanders M., Berry A., McQuillan J., Aslett M.A., Quail M.A.,
RA   Chukualim B., Capewell P., MacLeod A., Melville S.E., Gibson W.,
RA   Barry J.D., Berriman M., Hertz-Fowler C.;
RT   "The genome sequence of Trypanosoma brucei gambiense, causative agent of
RT   chronic human african trypanosomiasis.";
RL   PLoS Negl. Trop. Dis. 4:E658-E658(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC       Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004637};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004637}.
CC       Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Era GTPase family. {ECO:0000256|ARBA:ARBA00007921}.
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DR   EMBL; FN554974; CBH16924.1; -; Genomic_DNA.
DR   RefSeq; XP_011779188.1; XM_011780886.1.
DR   AlphaFoldDB; D0A5H3; -.
DR   GeneID; 23867374; -.
DR   KEGG; tbg:TbgDal_XI390; -.
DR   VEuPathDB; TriTrypDB:Tbg972.11.390; -.
DR   OrthoDB; 167240at2759; -.
DR   Proteomes; UP000002316; Chromosome 11.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   CDD; cd00880; Era_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR005662; GTPase_Era.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   NCBIfam; TIGR00231; small_GTP; 1.
DR   PANTHER; PTHR42698; GTPASE ERA; 1.
DR   PANTHER; PTHR42698:SF4; GTPASE ERA, MITOCHONDRIAL; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          95..217
FT                   /note="G"
FT                   /evidence="ECO:0000259|Pfam:PF01926"
SQ   SEQUENCE   382 AA;  43657 MW;  D072A48EE2FD0FE7 CRC64;
     MLSRTFSRLN TVYSRRRWEQ RIVSVLSEQK NANVDAVAQR FTRIYKERRF TPVEEAFPLR
     DTARWVGLND ESNSGSHINQ QSTLQQPPDA HKLRAVIVGT QNSGKTSLLN ALSLSHIGAV
     SNRSGVTREW TRGVATVHNT QLVLLDTPGI VICNGEKDRR RHAAPVARTW DAFTVTDLVM
     LTLPAGLGFV EPEQKTVARE VVHRASLRKM PVVLVITMMD RVQTPRHREL YFAMRTDLES
     LCLPIACVSE TSVKGGNGLV ELKDLLCRYA SPGDWEFFRN ETTDATPVDR VMELLRQCFF
     EVLPHEIPHQ MRHRIIGWTK KDSGTVEVIT EVFFDRPAYM FTFYAKLEAI CYRAQRIVER
     ELKGRYRFVF QAFITPGGMS CK
//