ID D0BKS1_9LACT Unreviewed; 140 AA.
AC D0BKS1;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=Putative pre-16S rRNA nuclease {ECO:0000256|HAMAP-Rule:MF_00651};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00651};
GN ORFNames=HMPREF0446_00556 {ECO:0000313|EMBL:EEW93674.1};
OS Granulicatella elegans ATCC 700633.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Granulicatella.
OX NCBI_TaxID=626369 {ECO:0000313|EMBL:EEW93674.1, ECO:0000313|Proteomes:UP000002939};
RN [1] {ECO:0000313|EMBL:EEW93674.1, ECO:0000313|Proteomes:UP000002939}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700633 {ECO:0000313|EMBL:EEW93674.1,
RC ECO:0000313|Proteomes:UP000002939};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Sibley C.D., Field T.R., Grinwis M., Eshaghurshan C.S.,
RA Surette M.G., Haas B., Nusbaum C., Birren B.;
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEW93674.1, ECO:0000313|Proteomes:UP000002939}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700633 {ECO:0000313|EMBL:EEW93674.1,
RC ECO:0000313|Proteomes:UP000002939};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Ward D., Feldgarden M., Gevers D., Sibley C.D., Field T.R.,
RA Grinwis M., Eshaghurshan C.S., Surette M.G., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Granulicatella elegans ATCC 700633.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Could be a nuclease involved in processing of the 5'-end of
CC pre-16S rRNA. {ECO:0000256|HAMAP-Rule:MF_00651}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00651}.
CC -!- SIMILARITY: Belongs to the YqgF HJR family. {ECO:0000256|HAMAP-
CC Rule:MF_00651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEW93674.1}.
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DR EMBL; ACRF02000013; EEW93674.1; -; Genomic_DNA.
DR RefSeq; WP_006702830.1; NZ_KI391971.1.
DR AlphaFoldDB; D0BKS1; -.
DR STRING; 626369.HMPREF0446_00556; -.
DR eggNOG; COG0816; Bacteria.
DR HOGENOM; CLU_098240_2_0_9; -.
DR OrthoDB; 9796140at2; -.
DR Proteomes; UP000002939; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0000967; P:rRNA 5'-end processing; IEA:UniProtKB-UniRule.
DR CDD; cd16964; YqgF; 1.
DR Gene3D; 3.30.420.140; YqgF/RNase H-like domain; 1.
DR HAMAP; MF_00651; Nuclease_YqgF; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR005227; YqgF.
DR InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR NCBIfam; TIGR00250; RNAse_H_YqgF; 1.
DR PANTHER; PTHR33317; POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR33317:SF4; POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN; 1.
DR Pfam; PF03652; RuvX; 1.
DR SMART; SM00732; YqgFc; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00651};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00651};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00651};
KW Reference proteome {ECO:0000313|Proteomes:UP000002939};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_00651}.
FT DOMAIN 1..103
FT /note="YqgF/RNase H-like"
FT /evidence="ECO:0000259|SMART:SM00732"
SQ SEQUENCE 140 AA; 15701 MW; FF2C8E474723E7D0 CRC64;
MRVMGLDVGS KTVGVAISDP LGWTAQGVET IVINEAASEF GFNRVVELVK EYEVEKIVIG
MPKNMNNTAG PRAEASQKYG RSLEKRLEIP IVFHDERLTT MQAERMLVEE ANVSRKKRKE
VIDKLAAVII LQNYLDLNIK
//
