ID D0EAC0_9VIRU Unreviewed; 127 AA.
AC D0EAC0;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE SubName: Full=RNA polymerase {ECO:0000313|EMBL:ACX54392.1};
DE Flags: Fragment;
GN Name=RdRp {ECO:0000313|EMBL:ACX54392.1};
OS HMO Astrovirus A.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC Stellavirales; Astroviridae; Mamastrovirus.
OX NCBI_TaxID=682382 {ECO:0000313|EMBL:ACX54392.1};
RN [1] {ECO:0000313|EMBL:ACX54392.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NI-281 {ECO:0000313|EMBL:ACX54392.1};
RX PubMed=19692544; DOI=10.1099/vir.0.014449-0;
RA Kapoor A., Li L., Victoria J., Oderinde B., Mason C., Pandey P.,
RA Zaidi S.Z., Delwart E.;
RT "Multiple novel astrovirus species in human stool.";
RL J. Gen. Virol. 90:2965-2972(2009).
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000256|ARBA:ARBA00004301};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004301}.
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DR EMBL; GQ441188; ACX54392.1; -; Genomic_RNA.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Ribosomal frameshifting {ECO:0000256|ARBA:ARBA00022758};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 10..125
FT /note="RNA-directed RNA polymerase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00680"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACX54392.1"
FT NON_TER 127
FT /evidence="ECO:0000313|EMBL:ACX54392.1"
SQ SEQUENCE 127 AA; 14972 MW; 0666C586B45E6C6F CRC64;
NEVFMAIKQF RYSCLAEEFK TEENLSIYKW YCESILDRYV MLPSGEVTKQ VRGNPSGQVS
TTMDNNLCNV FFQAFEYAYM HPDKDISQLM HDWEKVDSLI YGDDRLSTYP ELPEDYVDRV
VDMYATV
//
