ID D0KZX6_HALNC Unreviewed; 377 AA.
AC D0KZX6;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACX95999.1};
GN OrderedLocusNames=Hneap_1163 {ECO:0000313|EMBL:ACX95999.1};
OS Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus
OS neapolitanus).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Halothiobacillaceae; Halothiobacillus.
OX NCBI_TaxID=555778 {ECO:0000313|EMBL:ACX95999.1, ECO:0000313|Proteomes:UP000009102};
RN [1] {ECO:0000313|EMBL:ACX95999.1, ECO:0000313|Proteomes:UP000009102}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23641 / c2 {ECO:0000313|Proteomes:UP000009102};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Davenport K., Brettin T., Detter J.C., Han C.,
RA Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Kerfeld C., Cannon G., Heinhort S.;
RT "Complete sequence of Halothiobacillus neapolitanus c2.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001801; ACX95999.1; -; Genomic_DNA.
DR RefSeq; WP_012824035.1; NC_013422.1.
DR AlphaFoldDB; D0KZX6; -.
DR STRING; 555778.Hneap_1163; -.
DR KEGG; hna:Hneap_1163; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_1_4_6; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000009102; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009102};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..377
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003010093"
FT DOMAIN 71..277
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 377 AA; 40598 MW; 7227B447E41D0CBA CRC64;
MSFIDSTSAK KLPGVAALLA IASVLSACGG HDEHPASATQ LEMKTQAELF KVHDQSLPVF
ALFPGSVITS DQISISSRVM GYVRSVDVHE GQTVKTGETL LTIDSTDVTG AINQARAEVN
KAHAALSDAK NNYDRYSSLY KENAVPKQMY EQMQTAYKVA QSNYSAAQAG LKQAESQLTY
VKISAPFSGT ITSRMVDSGQ MASPGIPLLT LQGSGQKQVE VQLTSQAFAT LKLGEPVTVR
YTDFQGEQHE FQGLVERMVD ATDPVTHTHT VKIGVPESVN VRSGNYVVVE IAVAHETGML
VPLSAIHDRG GIRGVFVLDD QNRAWFRMVR LGHVIDGKQV ILSGLVPGER LVTKSDDRLQ
NGIVVTNASA DKEQPAS
//
