ID D0MX49_PHYIT Unreviewed; 1088 AA.
AC D0MX49;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Structural maintenance of chromosomes protein 5 {ECO:0000256|ARBA:ARBA00018687};
GN ORFNames=PITG_02755 {ECO:0000313|EMBL:EEY64212.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY64212.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC5 subfamily.
CC {ECO:0000256|ARBA:ARBA00010171}.
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DR EMBL; DS028120; EEY64212.1; -; Genomic_DNA.
DR RefSeq; XP_002907648.1; XM_002907602.1.
DR AlphaFoldDB; D0MX49; -.
DR STRING; 403677.D0MX49; -.
DR EnsemblProtists; PITG_02755T0; PITG_02755T0; PITG_02755.
DR GeneID; 9476775; -.
DR KEGG; pif:PITG_02755; -.
DR VEuPathDB; FungiDB:PITG_02755; -.
DR eggNOG; KOG0979; Eukaryota.
DR HOGENOM; CLU_004969_2_0_1; -.
DR InParanoid; D0MX49; -.
DR OMA; RFWTSQP; -.
DR OrthoDB; 232016at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR027131; SMC5.
DR PANTHER; PTHR45916; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR PANTHER; PTHR45916:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 20..1016
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT REGION 365..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 195..258
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 642..697
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 779..806
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1088 AA; 125317 MW; BF5D0690D6F3A31A CRC64;
MGDVMDGSSE GSDEYVDGSI YRVKLHNFLT YSDAEFYPGP RLNLILGPNG TGKSSIVCAL
CVGLAGSTKF VRHEKESGYT EIELFFERGN KVIRRNIFRD NKSTWQVNGK DSTLKHVAGI
MEAASIQIDN LCQFLPQDKV GEFSRMNAVQ LLKATENAIT DSDLATKHEE IIELQHSMSD
KGRELEHARA ALELKKSENA QRQKEVERIE DYEARIEETA VMEKKCLWLE FEKAKAEVEE
LKEEKLRCKE AINKERKEKI DPLVELLKKE QIKLEDVKAE YAMNFYSAVA TISVLTTCVR
VKTRKTEVDG EKKELVESIR KEKKHIENME GAQSQTLSDV KELRNQHNST RRKLERLERD
VADWHKEREG MANDDDLREQ KEQLERQQRA KDMEETEIRS KREALSRELS YIDSERRKVT
SKLEKLDNED VQRRLALQRA DPDCIRAADW VKSNQHRLKR KVWGPIALEM KLNETMHAKY
VEDTLPKWLL GALVAESYED YNTILREVNN VDSDRRIKAS IVIVENGTCH AVHRPYSPGQ
MDDYCQRYGM KGFLDELVAA PDIVHEALRA HGGLHTVMVG SQQTEDIINR GGQIFNDIAS
SERKSAFVTP YKKYVTSVSK YGNRNVTTRT NDLLNPRLLA ASTSNEDEKA EMKKILDDLE
ARERRIQVEI TDLKEQEKQY AEEKRKAQHR ITEIRSQRKA IIRLDDKITE GDNKIYSLKS
ELAQDVSSKE EALTRKLKNQ ASKQAQQIKH CLELSRKLFK TSAREVCLSL QLGTQQVRVE
FTQKHLKQTE TTLRNLKEAH KLAKDNLLTV ARRAMDVKRK AEEEAPWDDY EKRFSQLPDD
LDELLGKIEN NKAALECFRG DRTIRELYER VRDEIRDDEV HLADLESFVT DGEDKINGIK
GKWHADLKDV VEHIDTSFRE FFKDIGCVGE ILLDDEDPDV AKWGIQRRAQ FRKNTKLSTM
TAEEQSGGEK SVGTIMYLMA LQSLTKCPFR VVDEINQGMD VYNERKVFQR ITKSSCGSKL
PQYFLITPKL ITGLNYHRDT KVMVILNGPY NNIQQELWDP DRFVACGKQG KRKGDGAVNG
SSKKRIRA
//
