ID D0N415_PHYIT Unreviewed; 1108 AA.
AC D0N415;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Voltage-gated Ion Channel (VIC) Superfamily {ECO:0000313|EMBL:EEY69119.1};
GN ORFNames=PITG_05304 {ECO:0000313|EMBL:EEY69119.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY69119.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS028124; EEY69119.1; -; Genomic_DNA.
DR RefSeq; XP_002998973.1; XM_002998927.1.
DR AlphaFoldDB; D0N415; -.
DR EnsemblProtists; PITG_05304T0; PITG_05304T0; PITG_05304.
DR GeneID; 9462929; -.
DR KEGG; pif:PITG_05304; -.
DR VEuPathDB; FungiDB:PITG_05304; -.
DR eggNOG; KOG1420; Eukaryota.
DR HOGENOM; CLU_270080_0_0_1; -.
DR InParanoid; D0N415; -.
DR OMA; YRCKEIT; -.
DR OrthoDB; 67982at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 183..263
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 423..510
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 630..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..678
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1108 AA; 125624 MW; 4991B3FF67A66699 CRC64;
MRSARRWKRP VVRDLLRKFS KRMRRAIKRR MKGESRRQWI ERNLHDSEVG VMLDVVQCIL
SFVMVIAMIK LNWKNPDTNF TIGYLAIDTI NLVATLANFG LRFYSASNRR SFLLHWLSVV
EMICVLPLLV EFTTGTTDSI PHTHAFRLLM MLRVMRLLQF YRLLRLAKSA KLRQGLLICL
TTLCVIMCGG IFMQTIEYCD PVHKGTQISG ETCQDMTFLD AIYFVCITIA TVGFGDVAPK
TNLGKAFDVA LIFFAGALIP IQISGYSYIL SRETAFDKKY EPDKSTQHVL LCGEVENGAL
LFFLHNWLHK DEERRTRRKV VILAPTLPSN DLRRVLLHPD YEERVIYLQG SAMVAADLQR
AAAPTAEYCF VMVKKHSGTL DQNDTAANLI TCSVRKNNRH APLHVQVSKF DNTRHFHISG
ATAVICLEQL KLAFFGKCLW IRGLNPFFGN LIHKFSHTEE CRGYWLSDYL SGCEQKICEA
ALPPFLLNMP SYRALAVLFY REFGVPLVGL RTIEDTTAVY PVDEQLSDGN FLSVFFIGRG
NDIASKIEKM TPAIFARHAD IAPASLGMSA NRNIRTVATI LTAAIENKIP FGRRVSVGFG
RDRRISSTPD KPNVKRSLRL SMFSGRAMDK IAPVDREDDE ADEQAFENEE TPTLPSAEDN
RLDARRFTPR HTDSNHITRD ENYSLGNPSD AAESPVGRPS KPVMPVIALT PAELVKKATT
PRGRTKDPVI KPLSSRMPLS ARSARSTVER STRDQSVRES FMYPNDSHAS NWEPAPLLRP
SVAASGNLRS RIRHMSLCFR RDPPPITLSD HYVVCGTPSN YEDFLANLSD LNEKVSGVIF
ITQRQLTEKD FMAHQLHERL YFVRGSPLSM HVFHTARMMY ARSILIMSYC GMENTSSMDL
ENDLENKDEN MADVDAITTH RFITEALQNE ASRPERNGTN EKRPMPFIVA EMIRPSNVKF
LIDRNGSLFD AKAAANEPRQ RDLLKDVKFL DSSFFSPLYA SGHIYFSNFM DALMGSCSNQ
QLMIEMVTQL VISGNMSIKM PNRVQRSRHR LTQIPAPERY HFRPYALLDT MTLGIYRSAN
TATSPQYVLT NPPGDELVTP QDLLFVIK
//
