ID D0N8T0_PHYIT Unreviewed; 770 AA.
AC D0N8T0;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401};
GN ORFNames=PITG_07644 {ECO:0000313|EMBL:EEY53965.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY53965.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116}.
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DR EMBL; DS028128; EEY53965.1; -; Genomic_DNA.
DR RefSeq; XP_002904596.1; XM_002904550.1.
DR AlphaFoldDB; D0N8T0; -.
DR STRING; 403677.D0N8T0; -.
DR EnsemblProtists; PITG_07644T0; PITG_07644T0; PITG_07644.
DR GeneID; 9462685; -.
DR KEGG; pif:PITG_07644; -.
DR VEuPathDB; FungiDB:PITG_07644; -.
DR eggNOG; KOG1968; Eukaryota.
DR HOGENOM; CLU_003574_5_0_1; -.
DR InParanoid; D0N8T0; -.
DR OMA; LICNERN; -.
DR OrthoDB; 6297at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17748; BRCT_DNA_ligase_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 89..168
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..770
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 85757 MW; 7BB57448B8E375CB CRC64;
MRNEKNGRIK RKALAQKKAQ RVDSDSDFEM QPSDNEVKEV TPKKEPLKRL RRAVKADSDE
DEEMPEVKPE AKKEEGALKK VPAPCSGCLD GKTFAFSGVL ESLSREDAVH LVKSCGGSVA
NSITRSTKYL VIGSTLEQGG NVTDGSKYKE AVAKNVRILT QNEFYNLITE AATAQQTQDL
AAEKAKIKAE TGALKTSSKG NQKLNTSIND ELWTDKYKPQ TLNHMIGNIE LGKKLKTWLL
DWEAMHVKGT KKVPFSTKLS ENRGAKTVLL SGPPGIGKTT IANLVARECG FACTELNASD
TRSKKMLQTG LKDVLGTQAL QFGAASGEFK EKMHLARRVI IMDEVDGMSG GDRGGTAELI
QLLKKSKTPI ICICNDRQSQ KVRSLANHSF DLRMRRPTKV QIGKRLMEIG LNEGLHMEKN
AIEEAADRCG NDIRQLLTQM QRWRLTTTKI TYADMVNPSS QHNKDESLRL NPFSATQQIF
QRELSFDARN EAYFVDYDLM PLMVQENYIQ SIMNNRRSSD ENLEAAMHAS EFISESDLLN
TYVRVEQRWD LLTKQAAMNV GACVYSAGFI GHPEFSKWLG KNSSASKSKR LLSELSVRMR
AHASGSREVI RLDYVPYMKE ILLKKLLSGE DNIHEVIELL DECEISREDL TESMESFKLP
GVKRHSYSEL DTKAKTAFTR MYNKASHKSQ AVVEAVLGST TIKKARGKTA VAKDDGSGLP
PPSDAESEPE EEDVDVSKFQ KKPRGGAKRK APAATAKKAP RKTPAKKRRT
//
