ID D0NQ85_PHYIT Unreviewed; 771 AA.
AC D0NQ85;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=Phosphate acetyltransferase {ECO:0000256|ARBA:ARBA00021528};
DE EC=2.3.1.8 {ECO:0000256|ARBA:ARBA00012707};
DE AltName: Full=Phosphotransacetylase {ECO:0000256|ARBA:ARBA00031108};
GN ORFNames=PITG_15243 {ECO:0000313|EMBL:EEY62817.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY62817.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC acetyl-CoA from acetate: step 2/2. {ECO:0000256|ARBA:ARBA00004989}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS028152; EEY62817.1; -; Genomic_DNA.
DR RefSeq; XP_002898692.1; XM_002898646.1.
DR AlphaFoldDB; D0NQ85; -.
DR STRING; 403677.D0NQ85; -.
DR EnsemblProtists; PITG_15243T0; PITG_15243T0; PITG_15243.
DR GeneID; 9479059; -.
DR KEGG; pif:PITG_15243; -.
DR VEuPathDB; FungiDB:PITG_15243; -.
DR eggNOG; ENOG502QW25; Eukaryota.
DR HOGENOM; CLU_019723_3_0_1; -.
DR InParanoid; D0NQ85; -.
DR OMA; FFMCLAD; -.
DR OrthoDB; 1219096at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0016407; F:acetyltransferase activity; IEA:InterPro.
DR CDD; cd03109; DTBS; 1.
DR Gene3D; 3.40.50.10950; -; 1.
DR Gene3D; 3.40.1390.20; HprK N-terminal domain-like; 1.
DR Gene3D; 3.40.50.10750; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010766; DRTGG.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004614; P_AcTrfase.
DR InterPro; IPR042113; P_AcTrfase_dom1.
DR InterPro; IPR042112; P_AcTrfase_dom2.
DR InterPro; IPR002505; PTA_PTB.
DR InterPro; IPR028979; Ser_kin/Pase_Hpr-like_N_sf.
DR NCBIfam; TIGR00651; pta; 1.
DR PANTHER; PTHR43356; PHOSPHATE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43356:SF3; PHOSPHATE ACETYLTRANSFERASE; 1.
DR Pfam; PF13500; AAA_26; 1.
DR Pfam; PF07085; DRTGG; 1.
DR Pfam; PF01515; PTA_PTB; 1.
DR SUPFAM; SSF75138; HprK N-terminal domain-like; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 255..373
FT /note="DRTGG"
FT /evidence="ECO:0000259|Pfam:PF07085"
FT DOMAIN 425..743
FT /note="Phosphate acetyl/butaryl transferase"
FT /evidence="ECO:0000259|Pfam:PF01515"
SQ SEQUENCE 771 AA; 84260 MW; B2B7FDB2E7048D9C CRC64;
MWTLRHSLRR SVGMALPHRR ALTAAAISQG KVPINNLYVT STEVTKKTAP VLIGLAHVLE
QKFTKVGYFR PIQPSPDSSM ADHHVDVMKH QLELSKDVEE LYGVTSSRAM EAMLTGKGDD
IVEEILERYE ECRKGHDFMI IEGSQVSKHE SAMSWKINVD IAKAIGSPVL MVTDFGDTSA
SSNALLEEMV SRTVMGRDQA EAAGLNYLGT IANRVRAKDV ATLREDLKLK MGKKEIPFLG
FLPMDEIIAS KRLNEVTHQL GAKQLFGNSI ANDAVVTSAV VAASALKDLF AHLKKYKDGA
MIITSGDRSD LMLGLMVSRL PGVLPNISAI VLTNGNYPHS NTQEILKGVE ALDKTGLSLP
IFSTPNDTNS TADGFAKVST YILPSSKLKI DRSKQLFDEF VEKEMLIGEL DEGMVVSRSP
KQFQHFLFSK SRAVQRHIVL TEGEDIRVLQ AADQILRQNL SRITILGDPD EITVNAKMAN
LDLSRANIIR PVDSHLLDKY VDYFYAKRKH KGVTRELARD YCKDETYFGT LMVELGDADG
MVSGACHTTA NTIRPALQLI KTTPNRPIVS SIFFMCLKDG VRIYGDCAVN TDPSAQDLAQ
IAVTSAESAE AFGLIPKVAL LSYATGDSNS GPIIDKVREA TKMAQELRPD LDIYGPIQYD
AAVDESIAKT KLKAIPSGAK VGGQANVLIF PDLNTGNNTY KAVQQSTGCI AMGPMLQGLR
KPVNDLSRGA TVKDIVTTVA ITAIQADQVI LKREAENSKN QNGEFLESAT M
//
