ID D0P170_PHYIT Unreviewed; 672 AA.
AC D0P170;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=ATP-binding Cassette (ABC) Superfamily {ECO:0000313|EMBL:EEY54093.1};
GN ORFNames=PITG_20005 {ECO:0000313|EMBL:EEY54093.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY54093.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC {ECO:0000256|RuleBase:RU003690}.
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DR EMBL; DS028240; EEY54093.1; -; Genomic_DNA.
DR RefSeq; XP_002895945.1; XM_002895899.1.
DR AlphaFoldDB; D0P170; -.
DR EnsemblProtists; PITG_20005T0; PITG_20005T0; PITG_20005.
DR GeneID; 9469999; -.
DR KEGG; pif:PITG_20005; -.
DR VEuPathDB; FungiDB:PITG_20005; -.
DR eggNOG; KOG0065; Eukaryota.
DR eggNOG; KOG0626; Eukaryota.
DR HOGENOM; CLU_409104_0_0_1; -.
DR InParanoid; D0P170; -.
DR OrthoDB; 87827at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR001360; Glyco_hydro_1.
DR InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00232; Glyco_hydro_1; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:EEY54093.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000313|EMBL:EEY54093.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 71..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..100
FT /note="ABC-2 type transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01061"
SQ SEQUENCE 672 AA; 75450 MW; 729C7E7D724563C9 CRC64;
MFLFPRFGVI FGPTFYQLEA DSVKRINSHI GLIYNSMDFI GVINLMTVLE VTCAERAVFY
REHMSNYYGP LSYSLSLWFA EVPYLIFVIV LFVTIEYWLV VNVAVGALSC LFNLFSGYLL
PRPAMMAGYK WFTCLMPSSY SLAALVGVQF GEAQDVISVT DGGVTTEMTV AQYIEDTYDF
RPNRKYNFMV GLMVIWAVLQ MAIYLTFNEI VPRVVISVHT ERPPDQTQRK RARLANVFAD
DAPRCFPADF MFGSATASYQ VEGAWNEGGR TPSIWDDFCR THHRTKVVCA NVADAFYHRY
RDNVKLMVDT GLQSSRFSVS WSRAMNWNPE TKRMQLNPQG LAFYHALVDE LIANNIVPIL
TLGAGAPGLK KSDTFAYIVA HNVHAAVVKA FRDLKASSPP VLDQKARIGI TLNSDAAYSL
DERNPLDVAC SGKEDAVRTV LVPLTSGYWR LSGNHAGTSG RSLAEIHNRG DGAIEGIVQQ
QALSSSSWRP TQPVPTTKYG RFFLFHSGVV DATSSFIRDE SYRWIHELHT EHHLVGLKVD
TAHFTTSPLS ELEALHVPKL RLVFIKEHRQ GAISMVSQLG LFVLAAVGSK LIVYEFKSKQ
LIGCVLYDSA DTNAKRRYGR PDKKEEVLPG RLRAVPLFAT CYVAQKELAR CNRYHARGGH
HNLLTPRRHS CS
//
