ID   D0P1C8_PHYIT            Unreviewed;       190 AA.
AC   D0P1C8;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   RecName: Full=Calpain catalytic domain-containing protein {ECO:0000259|Pfam:PF00648};
GN   ORFNames=PITG_19676 {ECO:0000313|EMBL:EEY54158.1};
OS   Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY54158.1, ECO:0000313|Proteomes:UP000006643};
RN   [1] {ECO:0000313|Proteomes:UP000006643}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX   PubMed=19741609; DOI=10.1038/nature08358;
RG   The Broad Institute Genome Sequencing Platform;
RA   Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA   Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA   Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA   Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA   Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA   Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA   Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA   Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA   Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA   Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA   Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA   Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA   Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA   Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA   Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA   Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA   Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA   Nusbaum C.;
RT   "Genome sequence and analysis of the Irish potato famine pathogen
RT   Phytophthora infestans.";
RL   Nature 461:393-398(2009).
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DR   EMBL; DS028244; EEY54158.1; -; Genomic_DNA.
DR   RefSeq; XP_002895891.1; XM_002895845.1.
DR   AlphaFoldDB; D0P1C8; -.
DR   EnsemblProtists; PITG_19676T0; PITG_19676T0; PITG_19676.
DR   GeneID; 9469767; -.
DR   KEGG; pif:PITG_19676; -.
DR   VEuPathDB; FungiDB:PITG_19676; -.
DR   eggNOG; KOG0045; Eukaryota.
DR   HOGENOM; CLU_1430610_0_0_1; -.
DR   InParanoid; D0P1C8; -.
DR   OrthoDB; 142935at2759; -.
DR   Proteomes; UP000006643; Partially assembled WGS sequence.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR   Pfam; PF00648; Peptidase_C2; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT   DOMAIN          46..143
FT                   /note="Calpain catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00648"
SQ   SEQUENCE   190 AA;  21196 MW;  9A7518FC8D52F41F CRC64;
     MEAPEQVKKN SYAEVKSPNV KNAISLGQRE NVPVYFHAQG TCLLDRSRES KAASRISGVG
     ISPGEMRVGR LADAYVYGAL SILSTSQLAL SQVFPELSDD LVRPDLVEVG TVFPKEQQYN
     DEGVYAVRFW RNNRSRVVVV DGEHTEKLDE CRHSPTKRGP KLEHAHTPLF FEKLEALVMT
     HFGVSHAPYA
//