ID D0UMX7_ISCVE Unreviewed; 221 AA.
AC D0UMX7;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
DE Flags: Fragment;
OS Ischnura verticalis (Eastern forktail damselfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Palaeoptera; Odonata; Zygoptera; Coenagrionidae; Ischnura.
OX NCBI_TaxID=88053 {ECO:0000313|EMBL:ACY44093.1};
RN [1] {ECO:0000313|EMBL:ACY44093.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20147900; DOI=10.1038/nature08742;
RA Regier J.C., Shultz J.W., Zwick A., Hussey A., Ball B., Wetzer R.,
RA Martin J.W., Cunningham C.W.;
RT "Arthropod relationships revealed by phylogenomic analysis of nuclear
RT protein-coding sequences.";
RL Nature 463:1079-1083(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
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DR EMBL; GQ886520; ACY44093.1; -; mRNA.
DR AlphaFoldDB; D0UMX7; -.
DR UniPathway; UPA00109; UER00181.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd05016; SIS_PGI_2; 1.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035482; SIS_PGI_2.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 1.
PE 2: Evidence at transcript level;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACY44093.1"
FT NON_TER 221
FT /evidence="ECO:0000313|EMBL:ACY44093.1"
SQ SEQUENCE 221 AA; 24226 MW; FBD6BC1E2C8CF73B CRC64;
GRYSLWSAIG LSISLSIGYD NFEALLAGAH FMDNHFCTAP LEQNAPVILA LLGVWYHNFY
GAETHALLPY DQYLHRFAAY FQQGDMESNG KYVTRSGEVV SYTTGPIVWG EPGTNGQHAF
YQLIHQGTRL IPADFIAPVN THNPIKEGLH HMILLANFLA QTEALMKGKG KEEAQAELTK
AGLSGEALEK ILPHKVFVGN RPTNSIMVNA VTPFTLGALI A
//
