ID D0V546_CTEFE Unreviewed; 153 AA.
AC D0V546;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Chymotrypsin {ECO:0000313|EMBL:ACY24344.1};
DE Flags: Fragment;
OS Ctenocephalides felis (Cat flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Siphonaptera; Pulicidae; Archaeopsyllinae;
OC Ctenocephalides.
OX NCBI_TaxID=7515 {ECO:0000313|EMBL:ACY24344.1};
RN [1] {ECO:0000313|EMBL:ACY24344.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CFGFIM1_E01 {ECO:0000313|EMBL:ACY24344.1};
RC TISSUE=Midgut {ECO:0000313|EMBL:ACY24344.1};
RX PubMed=20017753; DOI=10.1111/j.1365-2583.2009.00978.x;
RA Dreher-Lesnick S.M., Ceraul S.M., Lesnick S.C., Gillespie J.J.,
RA Anderson J.M., Jochim R.C., Valenzuela J.G., Azad A.F.;
RT "Analysis of Rickettsia typhi-infected and uninfected cat flea
RT (Ctenocephalides felis) midgut cDNA libraries: deciphering molecular
RT pathways involved in host response to R. typhi infection.";
RL Insect Mol. Biol. 0:0-0(2009).
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DR EMBL; GU018011; ACY24344.1; -; mRNA.
DR AlphaFoldDB; D0V546; -.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24250; CHYMOTRYPSIN-RELATED; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}.
FT DOMAIN 20..153
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACY24344.1"
FT NON_TER 153
FT /evidence="ECO:0000313|EMBL:ACY24344.1"
SQ SEQUENCE 153 AA; 16798 MW; A56E308223417F4A CRC64;
LIIVLVFVLG ICSGSPHSRI ICGQNAKKNS APYMASVQLL DKIDGVEKLF HFCGGAIVND
RWILTAAHCL KGKDHLLDQL VIAIRLTNLS EGSTVYPGKK GILHEEYEHY DIIQDIALIK
VKSPIEFNEK VTTVKLGEDY VGGDVQLPLT GWG
//
