ID D1A222_THECD Unreviewed; 1502 AA.
AC D1A222;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Cell divisionFtsK/SpoIIIE {ECO:0000313|EMBL:ACY99675.1};
GN OrderedLocusNames=Tcur_4147 {ECO:0000313|EMBL:ACY99675.1};
OS Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=471852 {ECO:0000313|EMBL:ACY99675.1, ECO:0000313|Proteomes:UP000001918};
RN [1] {ECO:0000313|EMBL:ACY99675.1, ECO:0000313|Proteomes:UP000001918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX PubMed=21475583; DOI=10.4056/sigs.1453580;
RA Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL Stand. Genomic Sci. 1:13-22(2011).
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DR EMBL; CP001738; ACY99675.1; -; Genomic_DNA.
DR RefSeq; WP_012854458.1; NC_013510.1.
DR STRING; 471852.Tcur_4147; -.
DR KEGG; tcu:Tcur_4147; -.
DR eggNOG; COG1674; Bacteria.
DR HOGENOM; CLU_003134_6_0_11; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000001918; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd00060; FHA; 1.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000313|EMBL:ACY99675.1};
KW Cell division {ECO:0000313|EMBL:ACY99675.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000001918};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 238..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 649..859
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1005..1195
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 667..674
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1022..1029
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1502 AA; 159993 MW; 0F8F69857B152122 CRC64;
MRISLTVLTG RGPRDIVIDA DSEMTVGNAT QAIFAALEGD SAAFGASAGP GDRSQRALWA
NGRMLDPQAQ AVRELRDGTV VAIDRRAAAA TLLQEPTGLV EVRVVAGPAA GAVHRLGLGT
HTLGGRDADL IVDDPAIPPR SLRITVQRGS VEVEASSRTR AVLDGRRLEE RAAWPFGGML
AVGSTMLSLA PCTAPDAHLE PLPGGGLAFN RPPRIVPQAQ PARLEVPRRP ERGPRERLRL
FGALLFSAFG LVMAYVLGQW WWALLALSWP LIQVGEWLSD RLHGRKSYRR ALKEYQARSA
SFGDELEALR RRDEAERRAM WPDPAEILIT ATGPRRRLWE RRISDDDALH LRVGLADLPA
RIELVGDEEG TVPTPTARAV PVTLDVGELG VIGLTGPRAA SRALARWLVA QAAVLHSPRD
LAVVVLSARE DGAEHWNWVR WLPHCAPRRG EDCLALVGAD AESVARRVTE LAIRITERRR
DRHGGAGPLA GSPAEPADAP FNVLIVLDGA RALRRVPGMP QVLSRGPDYG LHAICIDDEE
RLLPEECAAV IAWQEDEGAP SIVRLRGPGL EGVGPVLADQ VPAAWAERVA RALAPVRDVS
RQDAAETMPE QVRLLDLLGM PDPTPEHVRA AWDASGGRTT RVPIGLAADG PFHIDLRTDG
PHGLIAGTTG AGKSELLQTL IAALAVANRP DEMTFVLIDY KGGAAFADCA ALPHTVGMVT
DLDGHLTERA LQSLSAELRR REEILLAAGA KDIDDYAELR DRAAAPRGPG RYARSRPAAS
HVELPPLPRL VLVIDEFAAL VSELPEFVAG LVDIGRRGRS LGVHLILATQ RPAGVVTAEI
RANTNLRIAL RVTDPQESTD VLDSPEAAQI SPATPGRCYV RSGTAVPQAV QSARIAGRRP
QGRGGAAPAK GKITVRDVPW GQLGRPLPET GPAEEDSGTV TDLAVLVGAI GEAAARAGIG
PQRSPWLDPL PERLRVSLRT AAGGSVVDVP PIEFGVTDLP ETQSRQALTL NLAADGHLYI
AGAAQSGRTT ALRTLAGSLA SSVSPFDVHL YAIDCGGGGL LPLVALPHCG AVVTRDQIDR
CERLLTALAN EVSRRQQLLA GAGFATLAEQ RATVASSDRL PWMVLLLDRW EGFVGAFEHY
DYGRLVDAFI RLLREGAAVG LRAVCTGDRT GLSGQISTVF DRRLVLRMAD PMDYGYAGLN
DRQVPASMPP GRALEQLGPG RPPRESQIGL LADDASGAAQ VAALQEIARA CTGRYGRLPR
RLRPLHVDEL PVRVTYAEAL ALDPDHLAPS PLWALVGVGG DTLGPVGVDL LNHGPAFMVA
GPPRSGRSTA LLTMVASLLD PAVGGGLVPV LLLTPRRSPL QALKGRPGVL GVLDADATED
DLLEAIGREH RYVVVVDDAE LLDDTDLDDA LRGVLRTARD GEHAVVLGGT TEDMNRGYRG
FLAEARRSRS GVLLSADSPD DGELFGLRLP RNSGALAGPT GRGLFVVQGA HFPIQVALPP
EE
//
