ID D1AAN7_THECD Unreviewed; 969 AA.
AC D1AAN7;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Transcriptional regulator, winged helix family {ECO:0000313|EMBL:ACY97047.1};
GN OrderedLocusNames=Tcur_1468 {ECO:0000313|EMBL:ACY97047.1};
OS Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=471852 {ECO:0000313|EMBL:ACY97047.1, ECO:0000313|Proteomes:UP000001918};
RN [1] {ECO:0000313|EMBL:ACY97047.1, ECO:0000313|Proteomes:UP000001918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX PubMed=21475583; DOI=10.4056/sigs.1453580;
RA Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL Stand. Genomic Sci. 1:13-22(2011).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; CP001738; ACY97047.1; -; Genomic_DNA.
DR AlphaFoldDB; D1AAN7; -.
DR STRING; 471852.Tcur_1468; -.
DR KEGG; tcu:Tcur_1468; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3903; Bacteria.
DR HOGENOM; CLU_004665_1_0_11; -.
DR Proteomes; UP000001918; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000001918}.
FT DOMAIN 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 249..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..281
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 969 AA; 102906 MW; 26A7AFA485096632 CRC64;
MVRFQVLGPL KADLGGRPVR LGGLRQRAVL AVLLIARGRI VSAEQIVSAV WEGSPPPSPT
TLHAYVSELR RALEPDRPAR APARLLVREG PGYALRITPD QLDAERFTDL AARGRRALEA
GAAAQAEELL GRALDLWQGP AYAEFTDAGF AIPEIARLED LRAGVQDDRV AAMIELGRHA
TAVGLLEAQV AEHPLRERGW ELLALALYRS GRQADALAAL RTVRRRLADE LGIEPGPALR
ALETAMLTQD PGLDPAPRHG AVPPGRPPAA EPVPPPAEPP AQWTPALRPE PARTGGNLPF
ALSAFVGRTE ELAMTGRLLA EHRLVTLTGT GGVGKTRLAL EAARRRSDPD GPWLVELAGL
QEETLLAAAV AAALGIPGVS TPDQLAAVLA GRELVLLLDN CEHLLRGAAE LVGALLARCG
GLRVLATSRE PLGVAGEAVY EVPPLEPAGD AAELFRRRAA AVLPGWSPDE AEQARIVRLC
AELDGIPLAI ELAAAQCRVL SIDQVADALA DRFAVLVGGA AGGPSRHRTL EEAVAWSHQL
LEPAERRLFH RLGVFAGGFD LEAAGAVAGV TPVLPPLSAL VRKSLLTVEP GSAPRRYRML
ETLRQYALRK LDPAELEAAR ERHRAWVLAR AEAADRRLRG PQGADLLAQL SGDLAEIRAT
FASAAAAGDG EYMLRLGAAM YWFCYRKGHI AEGLSWLSEA LAAVPDADPG LRARARVGLG
GLLYLNGQVR DAYEAALTAG QEARAAGDRI TEALTDIYRV YMGALAGVPL DVAELSRTAV
ERARATTEEW LVAEALMVQG MMARLAGDPS APQVLEEAIA VAQACGHGWS VGSALWAAMK
AALDRGDGPR TLELAKGLLV ISERDVDVTS WLVLLHTAAH ALVLTGRPES AAVLVGAVEG
IGRQVGFSPE KMDPLDGPRT SAAVRRALPA HEYRRHLARG RRMSRREVSA LLADLIAETT
AAAGRPGAR
//
