ID D1GKM6_9NEOP Unreviewed; 366 AA.
AC D1GKM6;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Elongation factor 1-alpha {ECO:0000256|RuleBase:RU000325};
DE Flags: Fragment;
GN Name=ef1a {ECO:0000313|EMBL:CAX38137.1};
GN Synonyms=EF1a {ECO:0000313|EMBL:CAX52902.1};
OS Orthopsyche thomasi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Trichoptera; Annulipalpia; Hydropsychoidea;
OC Hydropsychidae; Hydropsychinae; Orthopsyche.
OX NCBI_TaxID=486978 {ECO:0000313|EMBL:CAX38137.1};
RN [1] {ECO:0000313|EMBL:CAX52902.1}
RP NUCLEOTIDE SEQUENCE.
RA Johanson K.A., Espeland M.;
RT "Phylogeny of the Ecnomidae (Insecta: Trichoptera).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAX38137.1}
RP NUCLEOTIDE SEQUENCE.
RA Espeland M., Johanson K.A.;
RT "The effect of environmental diversification on species diversification in
RT New Caledonian caddisflies (Insecta: Trichoptera: Hydropsychidae).";
RL J. Biogeogr. 37:879-890(2010).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982, ECO:0000256|RuleBase:RU000325}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249,
CC ECO:0000256|RuleBase:RU000325}.
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DR EMBL; FM998462; CAX38137.1; -; Genomic_DNA.
DR EMBL; FN178827; CAX52902.1; -; Genomic_DNA.
DR AlphaFoldDB; D1GKM6; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:CAX38137.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000325};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000325};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:CAX38137.1}.
FT DOMAIN 1..196
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 333..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAX38137.1"
FT NON_TER 366
FT /evidence="ECO:0000313|EMBL:CAX38137.1"
SQ SEQUENCE 366 AA; 39909 MW; 187D20E1E1D433B2 CRC64;
QEMGKGSFKY AWVLDKLKAE RERGITIDIA LWKFETIRYY VTIIDAPGHR DFIKNMITGT
SQADCAVLIV AAGTGEFEAG ISKNGQTREH ALLAFTLGVK QLIVGVNKMD STEPAYSEPR
FEEIKKEVSS YIKKIGYNPA AVAFVPISGW HGDNMLEPSS KMPWFKGWNV ERKEGKAEGK
CLIEALDAIL PPARPTDKAL RLPLQDVYKI GGIGTVPVGR VETGILKPGT IVVFAPANLT
TEVKSVEMHH EALPEAMPGD NVGFNVKNVS VKELRRGYVA GDTKVNPPKG ASDFTAQVIV
LNHPGQIANG YTPVLDCHTA HIACKFAEIQ QKVDRRTGKS TEDNPKSIKS GDAAIVNLVP
SKPMCV
//
