ID D1KIU0_ROULA Unreviewed; 240 AA.
AC D1KIU0;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
DE Flags: Fragment;
GN Name=OR2 {ECO:0000313|EMBL:ACT90466.1};
OS Rousettus lanosus (Long-haired rousette) (Stenonycteris lanosus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Rousettus.
OX NCBI_TaxID=77222 {ECO:0000313|EMBL:ACT90466.1};
RN [1] {ECO:0000313|EMBL:ACT90466.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=19952139; DOI=10.1101/gr.099416.109;
RA Hayden S., Bekaert M., Crider T.A., Mariani S., Murphy W.J., Teeling E.C.;
RT "Ecological adaptation determines functional mammalian olfactory
RT subgenomes.";
RL Genome Res. 20:1-9(2010).
CC -!- FUNCTION: Putative odorant or sperm cell receptor.
CC {ECO:0000256|ARBA:ARBA00003929}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; GQ217311; ACT90466.1; -; Genomic_DNA.
DR AlphaFoldDB; D1KIU0; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26453; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR26453:SF115; OLFACTORY RECEPTOR-RELATED; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363047};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW Olfaction {ECO:0000256|ARBA:ARBA00022725, ECO:0000256|RuleBase:RU363047};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:ACT90466.1};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363047}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..240
FT /note="Olfactory receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003023767"
FT TRANSMEM 44..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 78..104
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 139..162
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 183..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 219..238
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT DOMAIN 1..236
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACT90466.1"
FT NON_TER 240
FT /evidence="ECO:0000313|EMBL:ACT90466.1"
SQ SEQUENCE 240 AA; 27080 MW; 4269103F738DCF6E CRC64;
FHSPMYFLLS HLATVDMAYA CNTVPQMLVN LLNPAKPISF AGCMTQTYLF LTFALTECLL
LLMMSYDRYV AICHPLRYSV IMSWSVCISL VVTSWACGSL LALAQMVLVL RLPFCGPHEI
NHFFCELLSV LKLACADTWL NQIIIFVACT FIVEGPLCLV LVSYTRILVA ILRIQSGDGR
RKAFSTCSSH LCVVGLFFGS AIVTYMAPKS RHPEEQQKIL FLFYSFFNPM LNPIIYSLRN
//
