ID D1NW52_9BIFI Unreviewed; 590 AA.
AC D1NW52;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Peptidase {ECO:0000313|EMBL:KFI60052.1};
DE EC=3.4.21.107 {ECO:0000313|EMBL:KFI60052.1};
DE SubName: Full=Trypsin {ECO:0000313|EMBL:EFA22338.1};
GN ORFNames=BGLCM_0071 {ECO:0000313|EMBL:KFI60052.1}, BIFGAL_04098
GN {ECO:0000313|EMBL:EFA22338.1};
OS Bifidobacterium gallicum DSM 20093 = LMG 11596.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=561180 {ECO:0000313|EMBL:EFA22338.1, ECO:0000313|Proteomes:UP000003656};
RN [1] {ECO:0000313|EMBL:EFA22338.1, ECO:0000313|Proteomes:UP000003656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20093 {ECO:0000313|EMBL:EFA22338.1,
RC ECO:0000313|Proteomes:UP000003656};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KFI60052.1, ECO:0000313|Proteomes:UP000029074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 11596 {ECO:0000313|EMBL:KFI60052.1,
RC ECO:0000313|Proteomes:UP000029074};
RA Ventura M., Milani C., Lugli G.A.;
RT "Genomics of Bifidobacteria.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA22338.1}.
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DR EMBL; ABXB03000004; EFA22338.1; -; Genomic_DNA.
DR EMBL; JGYW01000001; KFI60052.1; -; Genomic_DNA.
DR RefSeq; WP_006295556.1; NZ_JGYW01000001.1.
DR AlphaFoldDB; D1NW52; -.
DR STRING; 561180.BIFGAL_04098; -.
DR MEROPS; S01.494; -.
DR eggNOG; COG0265; Bacteria.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000003656; Unassembled WGS sequence.
DR Proteomes; UP000029074; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR43343; PEPTIDASE S12; 1.
DR PANTHER; PTHR43343:SF3; PROTEASE DO-LIKE 8, CHLOROPLASTIC; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KFI60052.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 161..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 416..481
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..138
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 60103 MW; 60225BEFAF34508B CRC64;
MAEEMNGVPT PPQSHDPYNG QSQADPATSA TTDGAASAAP ATSTEVSAQP TEIIETTVQE
QQTETMPTQP IFQQAPQYGA YAPTSQPVPH SAPTGVFAQQ NLQPTSPAPM GGNPYGGMAG
VPNGPVPPNG PGSPFGPANP NNPNNGNGPA MQDQPRTASN VVVAVVAALV SAALCLGIGF
MALTNGWVSV PQGNSLTSVS SNKSGSGSAK VEGGNAPDWI TVSNNVSPSV VAIQTQMSNG
SAKGSGAILD TEGHVVTNNH VVAGAERIQI NLDNGDIYEA KVVGTDKTTD LAVLQIQNPP
KDLKPITFAD SSQLAPGENV MAIGNPLGYD GTVTSGIISA LNRPVSVVDG NTQIVANAVQ
IDAAINPGNS GGPTFNAAGQ VIGINSSIAS NSSSESTAGS IGIGFAIPSN LVKRICEEII
KDGKAQHVAL GVTIKSATVT ADGVTRGGAQ VQSVVSGGPA DKAGIKAGDT IVAYDGNAVN
DNYSLLGFVR AAAMNSTAKI TLVRDGHTID VDVTFDRAEQ DVNGTNRQDS NNQNDQNGQN
GNRDQNNGQD QNGQNGQNGQ DGQDLNGQND QNRNGDRDSG NGFTDPFGLW
//
