ID D1PIB4_9FIRM Unreviewed; 376 AA.
AC D1PIB4;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Anaerobic sulfatase maturase {ECO:0000313|EMBL:EFB77582.1};
DE EC=1.1.99.- {ECO:0000313|EMBL:EFB77582.1};
GN ORFNames=SUBVAR_04079 {ECO:0000313|EMBL:EFB77582.1};
OS Subdoligranulum variabile DSM 15176.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Subdoligranulum.
OX NCBI_TaxID=411471 {ECO:0000313|EMBL:EFB77582.1, ECO:0000313|Proteomes:UP000003438};
RN [1] {ECO:0000313|EMBL:EFB77582.1, ECO:0000313|Proteomes:UP000003438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15176 {ECO:0000313|EMBL:EFB77582.1,
RC ECO:0000313|Proteomes:UP000003438};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFB77582.1}.
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DR EMBL; ACBY02000009; EFB77582.1; -; Genomic_DNA.
DR RefSeq; WP_007045526.1; NZ_GG704769.1.
DR AlphaFoldDB; D1PIB4; -.
DR STRING; 411471.SUBVAR_04079; -.
DR GeneID; 78307456; -.
DR eggNOG; COG0641; Bacteria.
DR HOGENOM; CLU_009273_10_0_9; -.
DR OrthoDB; 9808591at2; -.
DR Proteomes; UP000003438; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21120; SPASM_anSME; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR034485; Anaerobic_Cys-type_sulfatase-m.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR047207; SPASM_anSME.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR NCBIfam; TIGR03942; sulfatase_rSAM; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF3; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDF00289; anaerobic_Cys-type_sulfatase-m; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:EFB77582.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003438};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 1..229
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 376 AA; 42172 MW; 2378F6DDC7E5DD7E CRC64;
MPNVSLLVKP ASSLCNMRCR YCFYEDEAAN RSQASMGLMT RDTAGRMVQQ ALEAAGPSGR
LTIAFQGGEP TVAGLGFFRD FVEDLARYNT ARIPVSYALQ TNGLALDEDW AAFLARHRFL
VGVSVDGDKT LHDEFRVDAA GKGTWNRVQK NLAMLQRAGV ACNLLCVVTR RCAKSAVRVY
HALQKTGVRY LQFIPCLDPL GEPRGQRPWS LTPQDYGQFL CALFDEWYRD WETGNYTSVR
LFEDYVHMAM GLPPSTCASG GQCGAYYVVE ADGSVYPCDF YVLDEWKLGS LWETPLAELG
RSPRAEDFLR EGLDRPAACA DCRWQSLCRG GCKRDWTTDG SGERQNYYCP AFRQFFAHAE
DRLRRIAAAE AAARRR
//
