ID D2A7L5_SHIF2 Unreviewed; 193 AA.
AC D2A7L5;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Modulator of drug activity B {ECO:0000313|EMBL:ADA75399.1};
GN Name=mdaB {ECO:0000313|EMBL:ADA75399.1};
GN OrderedLocusNames=SFxv_3369 {ECO:0000313|EMBL:ADA75399.1};
OS Shigella flexneri serotype X (strain 2002017).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=591020 {ECO:0000313|EMBL:ADA75399.1, ECO:0000313|Proteomes:UP000001884};
RN [1] {ECO:0000313|EMBL:ADA75399.1, ECO:0000313|Proteomes:UP000001884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2002017 {ECO:0000313|EMBL:ADA75399.1,
RC ECO:0000313|Proteomes:UP000001884};
RX PubMed=19955273; DOI=10.1128/JCM.00614-09;
RA Ye C., Lan R., Xia S., Zhang J., Sun Q., Zhang S., Jing H., Wang L., Li Z.,
RA Zhou Z., Zhao A., Cui Z., Cao J., Jin D., Huang L., Wang Y., Luo X.,
RA Bai X., Wang Y., Wang P., Xu Q., Xu J.;
RT "Emergence of a new multidrug-resistant serotype X variant in an epidemic
RT clone of Shigella flexneri.";
RL J. Clin. Microbiol. 48:419-426(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the oxidoreductase MdaB family.
CC {ECO:0000256|ARBA:ARBA00037981}.
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DR EMBL; CP001383; ADA75399.1; -; Genomic_DNA.
DR RefSeq; WP_000065436.1; NC_017328.1.
DR AlphaFoldDB; D2A7L5; -.
DR KEGG; sfe:SFxv_3369; -.
DR PATRIC; fig|591020.3.peg.3624; -.
DR HOGENOM; CLU_083846_0_0_6; -.
DR Proteomes; UP000001884; Chromosome.
DR Gene3D; 3.40.50.360; -; 1.
DR InterPro; IPR003680; Flavodoxin_fold.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR PANTHER; PTHR46305; -; 1.
DR PANTHER; PTHR46305:SF3; NADPH:QUINONE OXIDOREDUCTASE MDAB; 1.
DR Pfam; PF02525; Flavodoxin_2; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630}.
FT DOMAIN 3..188
FT /note="Flavodoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF02525"
SQ SEQUENCE 193 AA; 21978 MW; A15B4E3686E4E8A8 CRC64;
MSNILIINGA KKFAHSNGQL NDTLTEVADG TLRDLGHDVR IVRADSDYNV KAEVQNFLWA
DVVIWQMPGW WMGAPWTVKK YIDDVFTEGH GTLYASDGRT RKDPSKKYGS GSLVQDKKYM
LSLTWNAPME AFTEKDQFFH GVGVDGVYLP FHKANQFLGM EPLPTFIAND VIKMPDVPRY
TEEYRKHLVE IFG
//
