ID   D2EH34_PEDAC            Unreviewed;       443 AA.
AC   D2EH34;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Xanthine permease {ECO:0000313|EMBL:EFA27279.1};
GN   Name=pbuX {ECO:0000313|EMBL:EFA27279.1};
GN   ORFNames=HMPREF9024_00096 {ECO:0000313|EMBL:EFA27279.1};
OS   Pediococcus acidilactici 7_4.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Pediococcus; Pediococcus acidilactici group.
OX   NCBI_TaxID=563194 {ECO:0000313|EMBL:EFA27279.1, ECO:0000313|Proteomes:UP000005738};
RN   [1] {ECO:0000313|EMBL:EFA27279.1, ECO:0000313|Proteomes:UP000005738}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=7_4 {ECO:0000313|EMBL:EFA27279.1,
RC   ECO:0000313|Proteomes:UP000005738};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Earl A., Feldgarden M., Young S.K., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA   Yandava C., Allen-Vercoe E., Strauss J., Ambrose C., McDonald J., Haas B.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Pediococcus acidilactici strain 7_4.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR   EMBL; GG730083; EFA27279.1; -; Genomic_DNA.
DR   AlphaFoldDB; D2EH34; -.
DR   HOGENOM; CLU_017959_8_2_9; -.
DR   Proteomes; UP000005738; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR017588; UacT-like.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   NCBIfam; NF037981; NCS2_1; 1.
DR   NCBIfam; TIGR03173; pbuX; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        84..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        180..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        249..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        329..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        357..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        388..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   443 AA;  46774 MW;  BFA266FDCCB9839B CRC64;
     MYFMKTNDSY ADAPITEITP QLTEGKAAVL GFQHLLAMYS GDVIVPLLIG GFLHFTAAQM
     TYLVSIDIFM CGIATLLQIR TTPLTGIGLP VVLGCAIQSV QPLERIGGGL GITAMYGAII
     ASGLFVILVA GLFSKIRGLF PPIVTGSIIT VIGFTLIPVA FEDIGGGNPA AQSYGDPKNL
     LVGLVTVAVI VLINVWARGF MRSIAVLIGI LVGTGIAALL GMVSFTPVLQ ASWFHFPRPF
     YFGVPTFNLS AILTMIMVTL TTMIESTGVF FALGDLVGKE ITQTDLKRGY RAEGVAAILG
     GVFNTFPYST FSENVGVLQL SGVKSRKPLY YAAGFLILLG LLPKAGAMAT IIPSSVLGGA
     MLVMFGIVGI QGVRILQKVN FNQTKDILIS ALSIGMGLGS TVDPQIYRAL PQACQMLLTN
     GIVVASITAV VLNLLFNGYD SSR
//