ID D2EIN1_PEDAC Unreviewed; 871 AA.
AC D2EIN1;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Glycosyl hydrolase family 38 N-terminal domain protein {ECO:0000313|EMBL:EFA27130.1};
GN ORFNames=HMPREF9024_00701 {ECO:0000313|EMBL:EFA27130.1};
OS Pediococcus acidilactici 7_4.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus; Pediococcus acidilactici group.
OX NCBI_TaxID=563194 {ECO:0000313|EMBL:EFA27130.1, ECO:0000313|Proteomes:UP000005738};
RN [1] {ECO:0000313|EMBL:EFA27130.1, ECO:0000313|Proteomes:UP000005738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7_4 {ECO:0000313|EMBL:EFA27130.1,
RC ECO:0000313|Proteomes:UP000005738};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Allen-Vercoe E., Strauss J., Ambrose C., McDonald J., Haas B.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Pediococcus acidilactici strain 7_4.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; GG730084; EFA27130.1; -; Genomic_DNA.
DR RefSeq; WP_004165322.1; NZ_GG730084.1.
DR AlphaFoldDB; D2EIN1; -.
DR HOGENOM; CLU_003442_2_1_9; -.
DR Proteomes; UP000005738; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10815; GH38N_AMII_EcMngB_like; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000313|EMBL:EFA27130.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 269..347
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 871 AA; 100528 MW; 869C5D4429167187 CRC64;
MKKIHVIHHT HWDFEWYFTR DEALIQFVYH MDEVFAALQA QKVDYYLLDG QMSILDDYLD
AYPEKSKEIK KWVNAGRLFI GPWYTQTDEL IITGESIVRN LSLGMKMAQR LGGAQPIGYL
PDSFGQGADM PKIYNGMNIK NAVFWRGLPK EKTANREFIW KSEDGSQVSV ANIKNGYFVG
VGLIEDDDAK NMMTTVVQGA SVDDVPLPVG GDQRYVDFNL KERISFYNQQ LDDAKLVESN
YVKYFQDLKQ HQNELDQVTG EFIDPSVSKI HRSIYSSRYD QKYLNDKVER RMIYQVEPLM
AMAERAGIPY KKALLEKIWK LIVRNHAHDS AGGCNSDKTN RMILARLVEA DQLSYSVVDY
LTRKITESDV NYGENTITFF NTLPYPITKR VKFQLSLKNP AFKLMKDDQK ITVDVEKVTK
EYHGQIKRDT SAYRDDDFYY KIDCSARINL PALQWQSFDV VASEAVPALL ENTTDKSISD
NHFKIEWVDG KLNLTNLNDQ TLVEDFMYIE DGGDEGDTYD YSPAYKNQVY RLDFKDAAVT
TRKGRVTSQL ILQGTWAVPV DLAARAENLR NQQINYQLEL ELDGSGRINH ELQIHNEAKD
HRMRVINRTN IYAKASYADT GFGYIERPVV DPHLKDWQAI GYHEEPTAIF PMIHYVNVHD
DERSVSFLTK GIKEYQITGA QNDRVALTLF RSVGYLGRPD LLRRPGVASG NQFTYIPTPD
SQLQKEMHFK WATYISKQFD PAEISKEFME YAVTNPNYQA QDLNQFTNTL KYFVMHPLKN
TIKAQPFFEL VDRRITFSSL TKSIDGTADL IRVVNLNKQK VQIDQLINLD KQYYINETDF
SGRIRKDLGY AASIEKISFQ PGEVKTFKIA R
//
