ID D2EJ05_PEDAC Unreviewed; 438 AA.
AC D2EJ05;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:EFA26477.1};
GN ORFNames=HMPREF9024_00767 {ECO:0000313|EMBL:EFA26477.1};
OS Pediococcus acidilactici 7_4.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus; Pediococcus acidilactici group.
OX NCBI_TaxID=563194 {ECO:0000313|EMBL:EFA26477.1, ECO:0000313|Proteomes:UP000005738};
RN [1] {ECO:0000313|EMBL:EFA26477.1, ECO:0000313|Proteomes:UP000005738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7_4 {ECO:0000313|EMBL:EFA26477.1,
RC ECO:0000313|Proteomes:UP000005738};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Allen-Vercoe E., Strauss J., Ambrose C., McDonald J., Haas B.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Pediococcus acidilactici strain 7_4.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG730085; EFA26477.1; -; Genomic_DNA.
DR RefSeq; WP_002829790.1; NZ_GG730085.1.
DR AlphaFoldDB; D2EJ05; -.
DR HOGENOM; CLU_003041_1_3_9; -.
DR Proteomes; UP000005738; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProt.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492}.
FT DOMAIN 25..195
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 221..365
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 375..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..438
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 438 AA; 48598 MW; 674B9C6BA01F3CEA CRC64;
MNDLFQQHFQ EKGFKQPTLI QERVAEPLRA GETVLGLSPT GSGKTLAFAL PLLEKVIPGN
GPQLLVLAPS QELAIQTTDV FREWASLINL KTTSITGGAN VQRQIERLKK KKPEIIVGTP
GRVLTLINER RLKVKEIQSL VIDEADEILT GEALEDVRQI EDQLPSDVQL SFFSATNDLA
IDDLQTWFGV TPQVIDVRAE DQTRGAVQHG WLTASPKNKP QILRQLSRVK KFQGLVFFNH
VATMEKITAL LKHEGVKVGK IAGHQVQIDR AAAMRRFKKK ELSLLMVTDV AARGLDIENL
PAVINYDIPR DATTYTHRVG RTGRMGQAGF VISLGDDHDI RNLKKILREL DQPAEKLAIA
NRQIMTATKA RQVAEQVADE KQTSAPVAEE APQKAPLRDV KTRKAATKVS PVASSKPKKK
GKKKHLKRKG KPRAKKSN
//
