ID D2GY53_AILME Unreviewed; 1170 AA.
AC D2GY53;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=WW and C2 domain containing 2 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=PANDA_001896 {ECO:0000313|EMBL:EFB30211.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB30211.1};
RN [1] {ECO:0000313|EMBL:EFB30211.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
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DR EMBL; GL192375; EFB30211.1; -; Genomic_DNA.
DR AlphaFoldDB; D2GY53; -.
DR InParanoid; D2GY53; -.
DR CDD; cd08680; C2_Kibra; 1.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037771; C2_WWC.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR14791; BOMB/KIRA PROTEINS; 1.
DR PANTHER; PTHR14791:SF26; PROTEIN WWC2; 1.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT DOMAIN 1..34
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 48..81
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 693..816
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 430..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 969..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1123..1170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 296..410
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 534..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1147..1163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB30211.1"
FT NON_TER 1170
FT /evidence="ECO:0000313|EMBL:EFB30211.1"
SQ SEQUENCE 1170 AA; 130011 MW; 493B96173F6340B8 CRC64;
LPLPRGWEEA RDYDGKVFYI DHNTRRTSWI DPRDRLTKPL SFADCVGDEL PWGWEAGFDP
QIGVYYIDHV NKTTQIEDPR KQWRGEQEKM LQDYLSVAQE ALRTQKELYH VKEQRLALAL
DEYVRLSDAY KEKSSSHTSL FSGSSSSTKY DPDILKAEIS TTRLRVKKLK RELSQMKQEL
LYKEQGFETL QQIDKKMSGG QSGYELSEAK AILTELKSIR KAISSGEKEK QDLMQSLAKL
QERFHSGRSI GTSEPDLTSG SVNSRLSLST QTLDAGSQTS TSADIGVRSR SNLAEKVRLS
LQYEEAKRSM ANLKIELSKL DSETWPGALD IEKEKLMLIN EKEELLKELQ FVTPQKRSQD
ELERLEAERQ RLEEELLSVR GPLSRALAER LKLEEQRKEL LQKLEEATKL TTYLHSQLKS
LSASTLSMSS GSSLGSLASS RGSLNTSSRG SLSSLSSGEL YYTSQSDQVD ADYQCKLDLL
LQEKGGYVPS GPITTIHENE VVKSPGQPGQ SGPCGAAAAA LGHTPPGHTP PRTEAPKSVT
SLSSRSSLSS LSPPGSPLVL EGTFPMSAHD VPLHRFTADF EDCELSSHFA DISLSESQIL
LDSHSGGVSQ SLSEDKDLGE CAREPLYEGT TDVEKSLPKR RVIHLLGEKT ACVSAAVSDE
SVAGDSGVYE AFVKQPSEVG DIPYGEGDAA IVETAQVQIG LRYDAKRSSF MVILAQLRNL
HAFLIPHTSK VYFRVALLPS STDVSCLFRT KVHPATESIL FNDMFRVAIS QTALQQKTLR
VDLCSVSKHR SEDCLAGTQI SLADLPFSNE IFTLWYNLLP SKQMSCKKND EENEDSVFQP
NQPLIHTRNL DAVSALLVRT SAELLAVKQE LAQEEEEEPP PGQEEEQRGP DGDWLTMLRE
ASDEIAAEQE ADVKLPEGSS RAGDLCSCPS APEAEEDAGR TDNSCAEDRG PEPPAGPCAL
VDKETNTDVA GDAGVAVRPK DRSGLSARQR PFVRSSVIVR SQTFSPGERS QYICRLNRSD
SDSSTLAKKS LFVRNSTERR SLRVKRAVCQ PVLRRTAPER PVRTSLDLEL DLQASLTRQS
RLNDELQALR GLRQKLEELK AQGETDLPPG VMEDERFQKL LKQAEKQAEQ SEEEQKQGLN
AEKLMRQASK DVCRLREQSR KVPRQVQSFR
//
