ID D2HE03_AILME Unreviewed; 176 AA.
AC D2HE03;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 {ECO:0000256|ARBA:ARBA00014109};
DE AltName: Full=Complex I-PDSW {ECO:0000256|ARBA:ARBA00030372};
DE AltName: Full=NADH-ubiquinone oxidoreductase PDSW subunit {ECO:0000256|ARBA:ARBA00032549};
DE Flags: Fragment;
GN ORFNames=PANDA_008983 {ECO:0000313|EMBL:EFB17177.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB17177.1};
RN [1] {ECO:0000313|EMBL:EFB17177.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- FUNCTION: Accessory subunit that is involved in the functional assembly
CC of the mitochondrial respiratory chain complex I. Complex I has an NADH
CC dehydrogenase activity with ubiquinone as an immediate electron
CC acceptor and mediates the transfer of electrons from NADH to the
CC respiratory chain. {ECO:0000256|ARBA:ARBA00024857}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004443}; Matrix side
CC {ECO:0000256|ARBA:ARBA00004443}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB10 subunit family.
CC {ECO:0000256|ARBA:ARBA00008317}.
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DR EMBL; GL192733; EFB17177.1; -; Genomic_DNA.
DR RefSeq; XP_002920232.1; XM_002920186.3.
DR AlphaFoldDB; D2HE03; -.
DR STRING; 9646.ENSAMEP00000008967; -.
DR GeneID; 100479731; -.
DR KEGG; aml:100479731; -.
DR CTD; 4716; -.
DR eggNOG; KOG4009; Eukaryota.
DR HOGENOM; CLU_112615_1_0_1; -.
DR InParanoid; D2HE03; -.
DR OMA; CKPILEQ; -.
DR OrthoDB; 2871654at2759; -.
DR TreeFam; TF105792; -.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:Ensembl.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Ensembl.
DR InterPro; IPR019377; NADH_UbQ_OxRdtase_su10.
DR InterPro; IPR039993; NDUFB10.
DR PANTHER; PTHR13094:SF1; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10; 1.
DR PANTHER; PTHR13094; NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT; 1.
DR Pfam; PF10249; NDUFB10; 1.
PE 3: Inferred from homology;
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 176
FT /evidence="ECO:0000313|EMBL:EFB17177.1"
SQ SEQUENCE 176 AA; 21005 MW; E55A2524E8B03F2B CRC64;
MPDSWDKDVY PEPPRRTPAP SPQTSLPNPI TYLTKAFDLL VDRPVTLVRE FIERQHAKNR
YYYYHREFRR VPDITECQEK DILCMFEAEM QWRRDYKVDQ EIVNIIQERL KACQQREGES
YRQNCAKELE QFTQVAKAYQ DRYHDLGAHY SARKCLAKQK QRMLAERKAA KEAAAA
//
