ID D2HGA9_AILME Unreviewed; 214 AA.
AC D2HGA9;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=N-6 adenine-specific DNA methyltransferase 1 {ECO:0000313|Ensembl:ENSAMEP00000008709.1};
DE Flags: Fragment;
GN Name=N6AMT1 {ECO:0000313|Ensembl:ENSAMEP00000008709.1};
GN ORFNames=PANDA_010012 {ECO:0000313|EMBL:EFB21503.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB21503.1};
RN [1] {ECO:0000313|EMBL:EFB21503.1, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000008709.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic/archaeal PrmC-related family.
CC {ECO:0000256|ARBA:ARBA00006149}.
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DR EMBL; GL192805; EFB21503.1; -; Genomic_DNA.
DR RefSeq; XP_002921160.1; XM_002921114.3.
DR STRING; 9646.ENSAMEP00000008709; -.
DR Ensembl; ENSAMET00000009079.2; ENSAMEP00000008709.1; ENSAMEG00000008279.2.
DR GeneID; 100464667; -.
DR KEGG; aml:100464667; -.
DR CTD; 29104; -.
DR eggNOG; KOG3191; Eukaryota.
DR GeneTree; ENSGT00390000013073; -.
DR HOGENOM; CLU_018398_6_0_1; -.
DR OMA; EWDDWME; -.
DR OrthoDB; 124743at2759; -.
DR TreeFam; TF314919; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0036009; F:protein-glutamine N-methyltransferase activity; IEA:Ensembl.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR004557; PrmC-related.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR NCBIfam; TIGR00537; hemK_rel_arch; 1.
DR PANTHER; PTHR45875; METHYLTRANSFERASE N6AMT1; 1.
DR PANTHER; PTHR45875:SF1; METHYLTRANSFERASE N6AMT1; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 29..126
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
FT NON_TER 214
FT /evidence="ECO:0000313|EMBL:EFB21503.1"
SQ SEQUENCE 214 AA; 23048 MW; FDEA124DBE4A3FBD CRC64;
MAVPRFRTPL HGHVGRGAFS NVYEPAEDTF LLLDALEAAA AELTGVEICL EVGSGSGVVS
AFLASIIGPQ ALYMCTDINP EAAACTLETA HCNKVHIQPV ITDLVKGLLP RLKEKVDLLV
FNPPYVVTPP EEVGSHGVEA AWAGGRNGRE VMDRLFPLAP DLLSPRGLFY LVTIKENNPE
EILKTMMTRG LQGTVALSRQ AGQELLSILK FTKS
//
