ID D2I382_AILME Unreviewed; 650 AA.
AC D2I382;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Protein PAT1 homolog 1 {ECO:0000256|ARBA:ARBA00041130};
DE AltName: Full=PAT1-like protein 1 {ECO:0000256|ARBA:ARBA00042386};
DE AltName: Full=Protein PAT1 homolog b {ECO:0000256|ARBA:ARBA00041591};
DE Flags: Fragment;
GN ORFNames=PANDA_019954 {ECO:0000313|EMBL:EFB23726.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB23726.1};
RN [1] {ECO:0000313|EMBL:EFB23726.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}. Nucleus speckle
CC {ECO:0000256|ARBA:ARBA00004324}. Nucleus, PML body
CC {ECO:0000256|ARBA:ARBA00004322}.
CC -!- SIMILARITY: Belongs to the PAT1 family.
CC {ECO:0000256|ARBA:ARBA00009138}.
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DR EMBL; GL194275; EFB23726.1; -; Genomic_DNA.
DR AlphaFoldDB; D2I382; -.
DR HOGENOM; CLU_009778_1_0_1; -.
DR InParanoid; D2I382; -.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
DR GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR InterPro; IPR039900; Pat1-like.
DR InterPro; IPR019167; PAT1_dom.
DR PANTHER; PTHR21551:SF2; PROTEIN PAT1 HOMOLOG 1; 1.
DR PANTHER; PTHR21551; TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1; 1.
DR Pfam; PF09770; PAT1; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 360..603
FT /note="mRNA decay factor PAT1"
FT /evidence="ECO:0000259|Pfam:PF09770"
FT REGION 35..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..221
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB23726.1"
FT NON_TER 650
FT /evidence="ECO:0000313|EMBL:EFB23726.1"
SQ SEQUENCE 650 AA; 72779 MW; F145168E3F7424DC CRC64;
PQPGSLNSSI WDGSEVLRRI RGPLLAQEMP TVSVLEYALP QRPPQGPEDD RDLSERALPR
RSTSPIIGSP PVRAVPIGTP PKQMAVPSFN QQILCPKPVH VRPPMPPRYP APYGERMSPN
QLCSVPNSSL LGHPFPPSVP PVLSPLQRAQ LLGGAQLPPG RMSPSQFARV PGFVGSPLAA
MNPKLLQGRV GQVLPPAPGF RAFFSAAPPA APPPPQQHSP GPGPHLQNLR SQAPMFRPDT
THLHPQHRRL LHQRQQQNRN QHRSLNGAGD RGSHRSSHQD HLRKDPYANL MLQREKDWVS
KIQMMQLQST DPYLDDFYYQ NYFEKLEKLS AAEEVQGEGP KKERTKLITP QVAKLEHAYK
PVQFEGSLGK LTVSSVNNPR KMIDAVVTSR SEDDETKEKQ VRDKRRKTLV IIEKTYSLLL
DVEDYERRCL LSLEEERPAL ADERKHKICS MYDNLRGKLP GQERPSDDHF VQIMCIRKGK
RMVARILPFL STEQAADILM TTARNLPFLI KKDAQDEVLP CLLSPFSLLL YHLPSVTVTS
LLQQLMNLPQ SAAAPAPSNP HLAAVLQNKF GLSLLLVVLS RGEDLQSSDP ATDPTQNNQW
TEVMFMATRE LLRIPQAALA KPISIPTNLV SLFSRYVDRQ KLNLLETKLQ
//
