ID D2PXP9_KRIFD Unreviewed; 1213 AA.
AC D2PXP9;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:ADB31691.1};
GN OrderedLocusNames=Kfla_2623 {ECO:0000313|EMBL:ADB31691.1};
OS Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Kribbellaceae; Kribbella.
OX NCBI_TaxID=479435 {ECO:0000313|EMBL:ADB31691.1, ECO:0000313|Proteomes:UP000007967};
RN [1] {ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Pukall R., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Kribbella flavida DSM 17836.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADB31691.1, ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RX PubMed=21304701;
RA Pukall R., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA Cheng J.-F., Lucas S., Chen F., Nolan M., LaButti K., Pati A., Ivanova N.,
RA Mavrommatis K., Mikhailova N., Pitluck S., Bruce D., Goodwin L., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C.D., Chen A., Palaniappan K., Chain P.,
RA Rohde M., Goeker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.-P., Brettin T.;
RT "Complete genome sequence of Kribbella flavida type strain (IFO 14399).";
RL Stand. Genomic Sci. 2:186-193(2010).
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DR EMBL; CP001736; ADB31691.1; -; Genomic_DNA.
DR RefSeq; WP_012920247.1; NC_013729.1.
DR AlphaFoldDB; D2PXP9; -.
DR STRING; 479435.Kfla_2623; -.
DR KEGG; kfl:Kfla_2623; -.
DR eggNOG; COG1409; Bacteria.
DR eggNOG; COG1520; Bacteria.
DR HOGENOM; CLU_269590_0_0_11; -.
DR OrthoDB; 256225at2; -.
DR Proteomes; UP000007967; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR Gene3D; 2.40.10.480; -; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.1120; Carboxypeptidase-like, regulatory domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR008969; CarboxyPept-like_regulatory.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR032285; Metallophos_N.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR34512; CELL SURFACE PROTEIN; 1.
DR PANTHER; PTHR34512:SF30; OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMB; 1.
DR Pfam; PF13620; CarboxypepD_reg; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16371; MetallophosN; 1.
DR Pfam; PF13360; PQQ_2; 2.
DR SMART; SM00564; PQQ; 8.
DR SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR SUPFAM; SSF117074; Hypothetical protein PA1324; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007967};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 69..144
FT /note="Calcineurin-like phosphoesterase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16371"
FT DOMAIN 159..329
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 1213 AA; 127564 MW; AED415927833BA00 CRC64;
MIRPTRTPAD RPPTTRWHKL LYGVTGGLAA LVIGVPLTGV IADAVDAPSA TVTGTVFVDE
DADHRQDAGE KPLAGVSVSD GQQIVVTDAQ GRYGLTIDVE RRNADLVFVT QPAGYSVGTD
DAMTPRFWRN LGQLAAGDTR KVNFGLRRDK VSAGGGFTFG NVADPHVNAQ LPEQITEINA
TRQDLAFIQV SGDLTNNATD AEFEFYKAST ANSKVPVWPA VGNHEYAAGA TYAARIDNYR
RHVGPEWYSF DYADRHFLVL ENNGAAPFAE QLEWVKADLA RNAGRGKRLV VLTHQPMNVP
FGSPSVYDEY GKVLEQYRAE LILVGHEHSN DVEPNSAFAG TAKHIQTASS SYTIDNSPRG
FRFVHMDNKS FDNPFRLYGA EKALTIVSPA PGTSVPLDRF PGIQVNAYDT TDAPVKVRYR
LDNRGWKQLR STGEFTWYAD LPGGTRTGSH TLEVEAADKT GATWRGTSNF TLTTDRAIRP
AAGADWNQHH GDAAHSGVAA AKVPAGQRLA WSYRTEGTFL TGSPAIVDGV VYVGTRDENG
DGNSALHAVE LATGRKLWTY PVPSSVHGSV AVSGGLVYVP TLRGTLFAVD AKTGQLKWRN
DPQAAPAGTN QRTYGYYGVT VADGKVLFPY QTRFGEAAAG ILLALDAKTG RRIWGTPMAG
NTMSDGTPAV ADGRVYVGNQ DGSIVIAYDL ATGRKLWTGT DTLGGWQDGV PSAGGGKVYI
GSNNGIVARD GATGAVRWSY TSTHPSLVNG GATPSAAAIK DNTVYMSFPS GAVTALDATT
GAVIWDQLLP GSLYRGGSFT SPALAGDTLF VGANSGGFYA LDALTGQPLW SQNIGTWVSA
GPAVSGNTVV AGAFDGNLYA FTPGGPSATP WPVVSGRVTR KADGAPAAAT TVSVVRDGAA
IGRTTTDAAG NYRVALPQGP GTYTLQVAQL GYATAAREVE VGPGGASGVD LEVSPVAVDA
SIGKRLPSGL VEGGPADVVI ENRKLALAVA KAYNDPQLNQ STTGKVLDLA ITGQPDQLDW
INLPYVSTAE PVGGNAWQQL QTRSTDVRIV ENTGSRAVVR VTGISAEHPG LKIVTTYTAT
ADEQFVTADT TFSNESAAGL SVWAGDAMDH DGPGSRSAVA GFPAITSGGP FSQVPTAKRW
IGQAGTSPDN QTYGLVYSAA SGPFTGYSQS NFTMSKFKLD LAAGAGHTIS RRIVAVSNGG
AADKFAVLDQ YAY
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