ID D2Q903_BIFDB Unreviewed; 343 AA.
AC D2Q903;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:ADB09289.1};
GN OrderedLocusNames=BDP_0623 {ECO:0000313|EMBL:ADB09289.1};
OS Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=401473 {ECO:0000313|EMBL:ADB09289.1, ECO:0000313|Proteomes:UP000008693};
RN [1] {ECO:0000313|EMBL:ADB09289.1, ECO:0000313|Proteomes:UP000008693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27534 / DSM 20436 / JCM 1195 / Bd1
RC {ECO:0000313|Proteomes:UP000008693};
RX PubMed=20041198; DOI=10.1371/journal.pgen.1000785;
RA Ventura M., Turroni F., Zomer A., Foroni E., Giubellini V., Bottacini F.,
RA Canchaya C., Claesson M.J., He F., Mantzourani M., Mulas L., Ferrarini A.,
RA Gao B., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Gupta R.S.,
RA Zhang Z., Beighton D., Fitzgerald G.F., O'Toole P.W., van Sinderen D.;
RT "The Bifidobacterium dentium Bd1 genome sequence reflects its genetic
RT adaptation to the human oral cavity.";
RL PLoS Genet. 5:E1000785-E1000785(2009).
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DR EMBL; CP001750; ADB09289.1; -; Genomic_DNA.
DR RefSeq; WP_012901953.1; NC_013714.1.
DR AlphaFoldDB; D2Q903; -.
DR STRING; 401473.BDP_0623; -.
DR KEGG; bde:BDP_0623; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_4_11; -.
DR Proteomes; UP000008693; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008693};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 343 AA; 37296 MW; 522EE737D60E03A7 CRC64;
MTRTTIADVA KAAGVSVSTV SRALRGLDRV NPETRERVEK EANRLHFSFS KSASSLASGK
TMRIAVLLPS EISSWFNSHA FEGIYEVMSK ADYDVVPYIV WTQEDLDRFF QNLPGNRNVD
AIIEASFDFD EAKKRVLGEL TIPVVGMNAP STHGLDAGVA IDDAAAMSAI VRFLKSLGHT
LAYIGQPVNA SPFICSDIVR EKGFLDAAKE CGYGDDDIII VPSLTHMDVQ NEQDIYSGIV
AQLLSAPKQP TGICVSVDAA AVPLLKELRR MGWRVPQDVS VVGFDDDPSA SIVDMTTMHQ
NPTEIGRIAA RKTLALLAGE TLEEPFSVIS TSLVLRSTTE RVH
//
