ID D2QFA5_SPILD Unreviewed; 734 AA.
AC D2QFA5;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Glutamate carboxypeptidase II {ECO:0000313|EMBL:ADB36582.1};
DE EC=3.4.17.21 {ECO:0000313|EMBL:ADB36582.1};
GN OrderedLocusNames=Slin_0518 {ECO:0000313|EMBL:ADB36582.1};
OS Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896 / Claus 1).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Spirosoma.
OX NCBI_TaxID=504472 {ECO:0000313|EMBL:ADB36582.1, ECO:0000313|Proteomes:UP000002028};
RN [1] {ECO:0000313|Proteomes:UP000002028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33905 / DSM 74 / LMG 10896
RC {ECO:0000313|Proteomes:UP000002028};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA Mikhailova N., Ovchinnikova G., Saunders E., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Tindal B., Schutze A., Schneider S.,
RA Goker M., Klenk H.-P., Eisen J.A.;
RT "The complete chromosome of Spirosoma linguale DSM 74.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADB36582.1, ECO:0000313|Proteomes:UP000002028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33905 / DSM 74 / LMG 10896
RC {ECO:0000313|Proteomes:UP000002028};
RX PubMed=21304700;
RA Lail K., Sikorski J., Saunders E., Lapidus A., Glavina Del Rio T.,
RA Copeland A., Tice H., Cheng J.-F., Lucas S., Nolan M., Bruce D.,
RA Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.-J.,
RA Jeffries C.D., Chain P., Brettin T., Detter J.C., Schuetze A., Rohde M.,
RA Tindall B.J., Goeker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.-P., Chen F.;
RT "Complete genome sequence of Spirosoma linguale type strain (1).";
RL Stand. Genomic Sci. 2:176-185(2010).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; CP001769; ADB36582.1; -; Genomic_DNA.
DR AlphaFoldDB; D2QFA5; -.
DR STRING; 504472.Slin_0518; -.
DR KEGG; sli:Slin_0518; -.
DR eggNOG; COG2234; Bacteria.
DR HOGENOM; CLU_005688_2_1_10; -.
DR Proteomes; UP000002028; Chromosome.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:UniProtKB-EC.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:ADB36582.1};
KW Hydrolase {ECO:0000313|EMBL:ADB36582.1};
KW Protease {ECO:0000313|EMBL:ADB36582.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..734
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003033701"
FT DOMAIN 156..219
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 342..542
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 607..715
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
SQ SEQUENCE 734 AA; 80038 MW; 7EF5699030698461 CRC64;
MYHPSLPKIT RRILALLISV TAAQAQPGQT PALSGFIPAR QAAQVKLESE FKAKQSSAAF
KAHLEKLSSV PHLTGSKENE QVRDYIAETM RKAGWQVDIY PHDVLLPKGP GEIAVEVVEP
VRQPLNIREF LFKEDKYSSD PRLTPGYNAW SGSGDVTAEV VYANYGRKED FEQLKAMGIS
VKGKIVLARY GGNFRGYKAQ FAQADGAVGV IIFTDPADSG YMRGLTFPEG PYYSESVIQR
GSLLTTPYTG DPLTPGEAAL PMDAKNTPKR LDQNAVGLHK IPVTPLPYGS ATEILKRMAG
ARPVPAGWQG GLPYTYRLEG GSALKVRLMV KQEKTIQRIY QVVGTLTGSE FPDEWIIAGC
HYDAWSYGAT DPNSGTAMLL SMTETMGKLA KAGQRPRRTI KVCHWDAEEP GVIGSAEWSE
QFRDELSQKA VAYMNYDAAV SGRTFGASAS PSMKKLIIEA TQAVQYPDSN KTVYQHWMGK
SAVGNPTRVT GSSAPALVAG EPTIGNLGGG SDHIAPYMHI GIPSLSAGME GPTLYHSQYD
DLYFYDKFAD PTYKMGPMME QVVGTMTMRL ANADLVPYDI ARYPTDLAIH LKAAERAIQA
YAPTYSINPL LNVVAELKKN ADACEMARQN YLKTGRTDKL VELNKELRLL ERSFIDPKGN
AFGGWYKSLY ASSDPNSGYA SWMLPGLLYE ASLKSTANLP DLEARYTKAI QTLSDKLLAL
SQGMAGPATV GSGK
//
