ID   D2QP13_SPILD            Unreviewed;      1021 AA.
AC   D2QP13;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Glycosyl hydrolase BNR repeat-containing protein {ECO:0000313|EMBL:ADB37619.1};
GN   OrderedLocusNames=Slin_1570 {ECO:0000313|EMBL:ADB37619.1};
OS   Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896 / Claus 1).
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Spirosoma.
OX   NCBI_TaxID=504472 {ECO:0000313|EMBL:ADB37619.1, ECO:0000313|Proteomes:UP000002028};
RN   [1] {ECO:0000313|Proteomes:UP000002028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33905 / DSM 74 / LMG 10896
RC   {ECO:0000313|Proteomes:UP000002028};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Mikhailova N., Ovchinnikova G., Saunders E., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Tindal B., Schutze A., Schneider S.,
RA   Goker M., Klenk H.-P., Eisen J.A.;
RT   "The complete chromosome of Spirosoma linguale DSM 74.";
RL   Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADB37619.1, ECO:0000313|Proteomes:UP000002028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33905 / DSM 74 / LMG 10896
RC   {ECO:0000313|Proteomes:UP000002028};
RX   PubMed=21304700;
RA   Lail K., Sikorski J., Saunders E., Lapidus A., Glavina Del Rio T.,
RA   Copeland A., Tice H., Cheng J.-F., Lucas S., Nolan M., Bruce D.,
RA   Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA   Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.-J.,
RA   Jeffries C.D., Chain P., Brettin T., Detter J.C., Schuetze A., Rohde M.,
RA   Tindall B.J., Goeker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.-P., Chen F.;
RT   "Complete genome sequence of Spirosoma linguale type strain (1).";
RL   Stand. Genomic Sci. 2:176-185(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001769; ADB37619.1; -; Genomic_DNA.
DR   AlphaFoldDB; D2QP13; -.
DR   STRING; 504472.Slin_1570; -.
DR   KEGG; sli:Slin_1570; -.
DR   eggNOG; COG4447; Bacteria.
DR   HOGENOM; CLU_004847_0_0_10; -.
DR   Proteomes; UP000002028; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd15482; Sialidase_non-viral; 2.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR   InterPro; IPR036278; Sialidase_sf.
DR   InterPro; IPR031778; Sortilin_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR   PANTHER; PTHR12106:SF27; VPS10 HOMOLOG 1-RELATED; 1.
DR   Pfam; PF15902; Sortilin-Vps10; 2.
DR   SUPFAM; SSF50939; Sialidases; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADB37619.1}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..1021
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003034085"
FT   DOMAIN          130..254
FT                   /note="Sortilin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15902"
FT   DOMAIN          527..671
FT                   /note="Sortilin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15902"
FT   REGION          798..821
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        803..818
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1021 AA;  113390 MW;  74095E2FF01D6D59 CRC64;
     MKYFAFYFLA ISCSLVLSNP LWAQPATKPD TAINPVFKGM AWRNIGPTRG GRSLGSAGSP
     SRKQEYYFGA VGGGLWKTTD GGQSWAPVTD GQLTSSSVGA VAVAESNPDV VYIGTGETQL
     RGNIMQGDGV YKSTNAGKTW TNIGLRNTQA IARVRIHPTN PDIVYVAALG HPYGPNEERG
     IFRTTDGGKS WKKVLYKSDK AGGIDLIIDR TNPNVLYASL WQVYRKPWKM WGGGGDSGLF
     KSTDGGETWT ELTRKPGMPK GTVGKIGVTV SPVDPNRVWA IVEAEDGGVY RSDDAGMTWK
     HVNDERKLRQ RAFYYSRIYA DPLDKNGVYC LNVDFFKSSD GGVKFNKSLK VPHGDNHDLW
     IDPADSTRMI TSNDGGAAVS VNGGKTWTDE NFPTAQLYHI TATNDFPYHV AGAQQDNTTV
     AVASEGWGNQ MARSNSIKKS EWTYEVGGGE SGYIAQDPKN PNIFYAGSQG ALLTRYDRTT
     GQTRDVQVYP RFFSGEPASA LPERWQWTYP IVFSPKDPNR LYVCSQHVWV STNEGQSWDK
     ISPDLTLADT ATLGKSGGVI TMDMNGPEIY ATVFALAPSY HDVNTIWAGS DDGLIHITRD
     HGKSWQKITP PDMPKHTRVS IIEASRHKPG TAYVAAKRYQ MDDRTPYLWK TDDYGKTWKK
     IITGLRADDY AHAIREDITR PGLLYAGMEH GVWVSFNDGE NWQPMQLKLP DTQISDIQVT
     EKDIVIGTHG RSIYVLDDVA PVREFTPDLA KKAVHLFKPY YAVRRVQPAV FQYYLAKKAD
     SVKIEILNAA GTLIQSFTGN KPSYPKDDED DDDSGKPKIK LPTTAAGLNR YEWDLRYPGA
     TYFKGMIMWG ARPTSGPLAL PGQYQVRLTV GDQTFTQPFE IKLDPRLKGV SQADVQEQFK
     MAMKLRDETS KANDAVIQIR AVKEKLAKQP DSPTNKKLKE QLNIIEENLY QIRNQSGQDP
     LNFPIKLNNR LAALWRSIES GDAKPTNGSY KVYEELTADL NKQLAELDTL LKTKTAKNIG
     M
//