ID D2RL55_ACIFV Unreviewed; 270 AA.
AC D2RL55;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN OrderedLocusNames=Acfer_1448 {ECO:0000313|EMBL:ADB47807.1};
OS Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP
OS 106432 / VR4).
OC Bacteria; Bacillota; Negativicutes; Acidaminococcales; Acidaminococcaceae;
OC Acidaminococcus.
OX NCBI_TaxID=591001 {ECO:0000313|EMBL:ADB47807.1, ECO:0000313|Proteomes:UP000001902};
RN [1] {ECO:0000313|EMBL:ADB47807.1, ECO:0000313|Proteomes:UP000001902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4
RC {ECO:0000313|Proteomes:UP000001902};
RX PubMed=21304687; DOI=10.4056/sigs.1002553;
RA Chang Y.J., Pukall R., Saunders E., Lapidus A., Copeland A., Nolan M.,
RA Glavina Del Rio T., Lucas S., Chen F., Tice H., Cheng J.F., Han C.,
RA Detter J.C., Bruce D., Goodwin L., Pitluck S., Mikhailova N., Liolios K.,
RA Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K., Land M.,
RA Hauser L., Jeffries C.D., Brettin T., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Acidaminococcus fermentans type strain
RT (VR4).";
RL Stand. Genomic Sci. 3:1-14(2010).
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
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DR EMBL; CP001859; ADB47807.1; -; Genomic_DNA.
DR RefSeq; WP_012938792.1; NZ_CP085936.1.
DR AlphaFoldDB; D2RL55; -.
DR STRING; 591001.Acfer_1448; -.
DR GeneID; 78335143; -.
DR KEGG; afn:Acfer_1448; -.
DR eggNOG; COG0503; Bacteria.
DR HOGENOM; CLU_088227_0_0_9; -.
DR OrthoDB; 4213751at2; -.
DR Proteomes; UP000001902; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR015265; PuR_N.
DR InterPro; IPR010078; PurR_Bsub.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01743; purR_Bsub; 1.
DR PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF09182; PuR_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001902};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 5..74
FT /note="Bacterial purine repressor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09182"
FT DOMAIN 118..254
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 270 AA; 29930 MW; 391A81EA44FD57D1 CRC64;
MARIKRLERI VALTKELNDH PFQLFPFSYF CEKFTVAKST LSEDVQTVRN GLSTYDLGII
ETVAGASGGV RFIPYHSPEA DNEFLWTLAK KLNDPSRLLP GGMIYMNDLL FDPQISFRLG
EIIMQRTLEL QPDYIMTVEA KGISLALATA RAFNIPMVMA RKEARITEGP AVSISYVSGS
SKKIQTMSLP RKALPPKSKV LVVDDFMRAG GTARGMQELA EEVGAEVVGT YLFIASREPE
KKIINEYASL MTLQGVDAET KAISIVPEML
//
