ID D2UFZ5_XANAP Unreviewed; 892 AA.
AC D2UFZ5;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=KdpD {ECO:0000313|EMBL:CBA17306.1};
GN OrderedLocusNames=XALc_2829 {ECO:0000313|EMBL:CBA17306.1};
OS Xanthomonas albilineans (strain GPE PC73 / CFBP 7063).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=380358 {ECO:0000313|EMBL:CBA17306.1, ECO:0000313|Proteomes:UP000001890};
RN [1] {ECO:0000313|EMBL:CBA17306.1, ECO:0000313|Proteomes:UP000001890}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GPE PC73 / CFBP 7063 {ECO:0000313|Proteomes:UP000001890};
RX PubMed=20017926; DOI=10.1186/1471-2164-10-616;
RA Pieretti I., Royer M., Barbe V., Carrere S., Koebnik R., Cociancich S.,
RA Couloux A., Darrasse A., Gouzy J., Jacques M.A., Lauber E., Manceau C.,
RA Mangenot S., Poussier S., Segurens B., Szurek B., Verdier V., Arlat M.,
RA Rott P.;
RT "The complete genome sequence of Xanthomonas albilineans provides new
RT insights into the reductive genome evolution of the xylem-limited
RT Xanthomonadaceae.";
RL BMC Genomics 10:616-616(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FP565176; CBA17306.1; -; Genomic_DNA.
DR RefSeq; WP_012917299.1; NC_013722.1.
DR AlphaFoldDB; D2UFZ5; -.
DR STRING; 380358.XALC_2829; -.
DR GeneID; 57878136; -.
DR KEGG; xal:XALC_2829; -.
DR PATRIC; fig|29447.3.peg.2787; -.
DR eggNOG; COG2205; Bacteria.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000001890; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001890};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 395..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 664..881
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 892 AA; 97810 MW; 65DE78713F8BC5F3 CRC64;
MSDLRTQQAD ALIGELKRER GGRLTVFLGA APGVGKTYAM LSRARQLQQQ GSVLVIGVVE
THGRVETAAL LEGLTVQPRR RVEYRGRTLD EMDLDALLAL RPPLVLVDEL AHRNAPGSRH
ERRWQDVEEL LDAGIDVYST VNIQHLESLN DVVHRITGVR VSETVPDAMF DRLRDIVLVD
LPPRELIERL QQGKVYLPEQ AGQALQAFFS PSNLAALREL AMQTAADRVD NDLRDVQAAQ
GRPGLALRRR VMVAIDGRGQ SDYLVRVARR VAERRGSPWT VVTVQTQAQP EEAWQLEIDR
AFALARRLGG DAALLRGSSV ADALLDHAAR NGVSTLLLGR TRERPLARMI NRTLTQQLLQ
RGAHYELVII SSPEARARSR RRWRSPGHWL SRDDLAFAMV ASALAVVVAW IAERWVGIDD
LSMVFIVAVV MVAAKTRMAA AVLAALLSFF GYNFFFIEPR FTFQIGTRQG VVTVLLFLVA
ALVAGRLASR LRSQVLALRA ANAQTTALQR LGRELTSAAD LGQVLDAGRH ALSTTLDAEA
WVRLQPLEAA HAGADDYAPS MAAVDRSAAD WAQRHGQATG RFTDTLAGAS WWFLPVRHER
GAIGVVGLRF AAGVQRPGLE QQRLAEAMVE DIGQAALRTR LVADLESARV SGETEHLRSA
LLSSVSHDLR SPLAAMIGAA SSLSSYGQAM SAEDRRSLLD TIQMEGERLD RYIQNLLDMT
RLGHNGLTLN RDWIGVDELI GSAARRLQRY QPEVLLDIVL AADLPTLWVH PALVEQAVFN
VLENAAKFSP PDTAIRVAAM MVEGRLRIDI ADRGPGIPED ERARIFDMFY SVERGDRGRH
GTGLGLTICQ GMIGAHGGSV EALPGPDGRG TTIRITLPLI EPAAPPRRPD AD
//
